Ma2 antibody and multiple mononeuropathies

Anti-Ma2 antibodies belong to a family of onconeuronal antibodies that target proteins expressed in brain, testis and several tumors. Previously observed in patients presenting with limbic encephalitis, they seem to be associated with several other paraneoplastic syndromes. We report the case of a 7...

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Bibliographic Details
Published in:Revue neurologique 2008-06, Vol.164 (6-7), p.608-611
Main Authors: Ayrignac, X, Castelnovo, G, Landrault, E, Fayolle, H, Pers, Y-M, Honnorat, J, Campello, C, Figarella-Branger, D, Labauge, P
Format: Article
Language:fre
Subjects:
Aged
Antibodies, Neoplasm - analysis
Antigens, Neoplasm - immunology
Biomarkers - analysis
Carcinoma, Non-Small-Cell Lung - classification
Carcinoma, Non-Small-Cell Lung - diagnostic imaging
Carcinoma, Non-Small-Cell Lung - immunology
Female
Hereditary Sensory and Motor Neuropathy - diagnostic imaging
Hereditary Sensory and Motor Neuropathy - etiology
Hereditary Sensory and Motor Neuropathy - immunology
Humans
Lung Neoplasms - classification
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - immunology
Magnetic Resonance Imaging
Nerve Tissue Proteins - immunology
Radiography, Thoracic
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Summary:Anti-Ma2 antibodies belong to a family of onconeuronal antibodies that target proteins expressed in brain, testis and several tumors. Previously observed in patients presenting with limbic encephalitis, they seem to be associated with several other paraneoplastic syndromes. We report the case of a 73-year-old woman presenting sensory and motor neuropathy associated with non-small-cell lung cancer who had Ma2-antibodies.
ISSN:0035-3787
DOI:10.1016/j.neurol.2008.03.005