Survival of patients with colorectal carcinoma : Possible prognostic value of tissular carbohydrate antigen 19.9 determination

An important goal of serum tumor marker research is to provide a test for detecting cancer in early stages. Expression of carbohydrate antigen (CA) 19.9 has been described in various malignancies. The possible prognostic value measuring cytosol CA 19.9 expression in tumors was evaluated in a study o...

Full description

Saved in:
Bibliographic Details
Published in:Cancer 1999-11, Vol.86 (9), p.1675-1681
Main Authors: MORALES-GUTIERREZ, C, VEGH, I, COLINA, F, GOMEZ-CAMARA, A, GARCIA-CARRANZA, A, LANDA, J. I, BALLESTEROS, D, CARREIRA, P. E, ENRIQUEZ-DE-SALAMANCA, R
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
CA-19-9 Antigen
Colonic Neoplasms - diagnosis
Colonic Neoplasms - epidemiology
Colonic Neoplasms - metabolism
Disease Progression
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Lymph Nodes - pathology
Male
Medical sciences
Middle Aged
Multivariate Analysis
Prognosis
Rectal Neoplasms - diagnosis
Rectal Neoplasms - epidemiology
Rectal Neoplasms - metabolism
Recurrence
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An important goal of serum tumor marker research is to provide a test for detecting cancer in early stages. Expression of carbohydrate antigen (CA) 19.9 has been described in various malignancies. The possible prognostic value measuring cytosol CA 19.9 expression in tumors was evaluated in a study of 63 colorectal carcinoma (CRC) patients who were followed for at least 2 years. CA 19.9 expression in cytosol was determined by enzyme-linked immunoadsorbant assay, and measurement of this protein achieved by quantitative assay. Mean levels of cytosol CA 19.9 found in tumor samples were significantly higher than those in nontumoral areas in CRC patients (P
ISSN:0008-543X
1097-0142
DOI:10.1002/(SICI)1097-0142(19991101)86:9<1675::AID-CNCR8>3.0.CO;2-9