The Effect of the Binge Drinking Session on the Activity of Salivary, Serum and Urinary β-Hexosaminidase: Preliminary Data

Our report is the first to show that an acute ingestion (6 h) of a relatively large, yet tolerable dose of alcohol (120–160 g), significantly increases activity of total serum β-hexosaminidase (total β-HEX), β-HEX A and β-HEX B isoenzymes, as well as salivary total β-HEX and urinary β-HEX A, in eigh...

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Bibliographic Details
Published in:Alcohol and alcoholism (Oxford) 2008-07, Vol.43 (4), p.446-450
Main Authors: Waszkiewicz, Napoleon, Szajda, Sławomir Dariusz, Jankowska, Anna, Kępka, Alina, Dobryniewski, Jacek, Szulc, Agata, Zwierz, Krzysztof
Format: Article
Language:English
Subjects:
Addictive behaviors
Adult
Adult and adolescent clinical studies
Alcohol Drinking - metabolism
Alcohol Drinking - physiopathology
Alcoholism
Alcoholism and acute alcohol poisoning
beta-N-Acetylhexosaminidases - analysis
beta-N-Acetylhexosaminidases - blood
beta-N-Acetylhexosaminidases - urine
Biological and medical sciences
Humans
Male
Medical sciences
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Saliva - chemistry
Severity of Illness Index
Toxicology
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Summary:Our report is the first to show that an acute ingestion (6 h) of a relatively large, yet tolerable dose of alcohol (120–160 g), significantly increases activity of total serum β-hexosaminidase (total β-HEX), β-HEX A and β-HEX B isoenzymes, as well as salivary total β-HEX and urinary β-HEX A, in eight infrequent binge drinkers. An increase in the activity of serum and urinary total HEX is mainly due to its secretory isoenzyme β-HEX A.
ISSN:0735-0414
1464-3502
DOI:10.1093/alcalc/agn027