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Cost comparison of sevoflurane with isoflurane anesthesia in arthroscopic menisectomy surgery
To determine the "real world" cost of sevoflurane compared with isoflurane in balanced general anesthesia for daycare arthroscopic menisectomy, we prospectively investigated perioperative drug requirement and expense as well as recovery time. Following intravenous induction, 40 consenting...
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| Published in: | Canadian journal of anaesthesia 1999-11, Vol.46 (11), p.1008-1013 |
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| cites | cdi_FETCH-LOGICAL-c375t-13f265a96158242b9404e77eab671662c2d3e7ab5b60670880ab3b39ae7ac5393 |
| container_end_page | 1013 |
| container_issue | 11 |
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| container_title | Canadian journal of anaesthesia |
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| creator | RIES, C. R AZMUDEH, A FRANCIOSI, L. G SCHWARZ, S. K. W MACLEOD, B. A |
| description | To determine the "real world" cost of sevoflurane compared with isoflurane in balanced general anesthesia for daycare arthroscopic menisectomy, we prospectively investigated perioperative drug requirement and expense as well as recovery time.
Following intravenous induction, 40 consenting adult patients randomly received either sevoflurane- or isoflurane-based anesthesia with a standardized gas inflow rate of 3 l x min. Recovery was assessed in the postanesthetic recovery room (PARR) in a double-blind manner at 15 min intervals using the Aldrete scoring system until patients met discharge criteria.
Patient demographics, anesthetic duration, volatile potency and adjunct drug requirements were similar in the two groups. Total perioperative drug cost per patient was CAN$38.10+/-10.13 (mean +/- SD) for the sevoflurane group and $23.87+/-6.59 for the isoflurane group (P |
| doi_str_mv | 10.1007/BF03013193 |
| format | article |
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Following intravenous induction, 40 consenting adult patients randomly received either sevoflurane- or isoflurane-based anesthesia with a standardized gas inflow rate of 3 l x min. Recovery was assessed in the postanesthetic recovery room (PARR) in a double-blind manner at 15 min intervals using the Aldrete scoring system until patients met discharge criteria.
Patient demographics, anesthetic duration, volatile potency and adjunct drug requirements were similar in the two groups. Total perioperative drug cost per patient was CAN$38.10+/-10.13 (mean +/- SD) for the sevoflurane group and $23.87+/-6.59 for the isoflurane group (P<0.01). Although the nonvolatile drug cost was comparable between the two groups, the volatile drug cost per patient was $19.40+/-8.80 for sevoflurane and $4.50+/-1.90 for isoflurane (P<0.01). This four-fold sevoflurane-to-isoflurane cost difference was the product of two ratios, both based on the volume of liquid anesthetic: the ratio of consumption, 2.1; and the ratio of institutional price, 2.1. Intraoperative hemodynamic response, time until discharge from the PARR and incidences of postoperative nausea and vomiting did not significantly differ between the two groups.
When used to maintain equipotent balanced general anesthesia for daycare arthroscopic menisectomy, volatile consumption and cost were greater for sevoflurane compared with isoflurane. Nonvolatile perioperative drug cost and recovery times were similar, however, in the two groups.</description><identifier>ISSN: 0832-610X</identifier><identifier>EISSN: 1496-8975</identifier><identifier>DOI: 10.1007/BF03013193</identifier><identifier>PMID: 10566918</identifier><identifier>CODEN: CJOAEP</identifier><language>eng</language><publisher>Toronto, ON: Canadian Anesthesiologists' Society</publisher><subject>Adult ; Aged ; Anesthesia ; Anesthesia, Inhalation - economics ; Anesthetics, Inhalation - pharmacology ; Anesthetics. Neuromuscular blocking agents ; Arthroscopy - economics ; Biological and medical sciences ; Costs and Cost Analysis ; Double-Blind Method ; Female ; Humans ; Isoflurane - pharmacology ; Male ; Medical sciences ; Menisci, Tibial - surgery ; Methyl Ethers - pharmacology ; Middle Aged ; Neuropharmacology ; Pharmacology. Drug treatments ; Prospective Studies ; Surgery</subject><ispartof>Canadian journal of anaesthesia, 1999-11, Vol.46 (11), p.1008-1013</ispartof><rights>2000 INIST-CNRS</rights><rights>Canadian Anesthesiologists 1999.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-13f265a96158242b9404e77eab671662c2d3e7ab5b60670880ab3b39ae7ac5393</citedby><cites>FETCH-LOGICAL-c375t-13f265a96158242b9404e77eab671662c2d3e7ab5b60670880ab3b39ae7ac5393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1187313$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10566918$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RIES, C. R</creatorcontrib><creatorcontrib>AZMUDEH, A</creatorcontrib><creatorcontrib>FRANCIOSI, L. G</creatorcontrib><creatorcontrib>SCHWARZ, S. K. W</creatorcontrib><creatorcontrib>MACLEOD, B. A</creatorcontrib><title>Cost comparison of sevoflurane with isoflurane anesthesia in arthroscopic menisectomy surgery</title><title>Canadian journal of anaesthesia</title><addtitle>Can J Anaesth</addtitle><description>To determine the "real world" cost of sevoflurane compared with isoflurane in balanced general anesthesia for daycare arthroscopic menisectomy, we prospectively investigated perioperative drug requirement and expense as well as recovery time.
Following intravenous induction, 40 consenting adult patients randomly received either sevoflurane- or isoflurane-based anesthesia with a standardized gas inflow rate of 3 l x min. Recovery was assessed in the postanesthetic recovery room (PARR) in a double-blind manner at 15 min intervals using the Aldrete scoring system until patients met discharge criteria.
Patient demographics, anesthetic duration, volatile potency and adjunct drug requirements were similar in the two groups. Total perioperative drug cost per patient was CAN$38.10+/-10.13 (mean +/- SD) for the sevoflurane group and $23.87+/-6.59 for the isoflurane group (P<0.01). Although the nonvolatile drug cost was comparable between the two groups, the volatile drug cost per patient was $19.40+/-8.80 for sevoflurane and $4.50+/-1.90 for isoflurane (P<0.01). This four-fold sevoflurane-to-isoflurane cost difference was the product of two ratios, both based on the volume of liquid anesthetic: the ratio of consumption, 2.1; and the ratio of institutional price, 2.1. Intraoperative hemodynamic response, time until discharge from the PARR and incidences of postoperative nausea and vomiting did not significantly differ between the two groups.
When used to maintain equipotent balanced general anesthesia for daycare arthroscopic menisectomy, volatile consumption and cost were greater for sevoflurane compared with isoflurane. Nonvolatile perioperative drug cost and recovery times were similar, however, in the two groups.</description><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia</subject><subject>Anesthesia, Inhalation - economics</subject><subject>Anesthetics, Inhalation - pharmacology</subject><subject>Anesthetics. 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Neuromuscular blocking agents</topic><topic>Arthroscopy - economics</topic><topic>Biological and medical sciences</topic><topic>Costs and Cost Analysis</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Isoflurane - pharmacology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Menisci, Tibial - surgery</topic><topic>Methyl Ethers - pharmacology</topic><topic>Middle Aged</topic><topic>Neuropharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Prospective Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RIES, C. R</creatorcontrib><creatorcontrib>AZMUDEH, A</creatorcontrib><creatorcontrib>FRANCIOSI, L. G</creatorcontrib><creatorcontrib>SCHWARZ, S. K. W</creatorcontrib><creatorcontrib>MACLEOD, B. 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Following intravenous induction, 40 consenting adult patients randomly received either sevoflurane- or isoflurane-based anesthesia with a standardized gas inflow rate of 3 l x min. Recovery was assessed in the postanesthetic recovery room (PARR) in a double-blind manner at 15 min intervals using the Aldrete scoring system until patients met discharge criteria.
Patient demographics, anesthetic duration, volatile potency and adjunct drug requirements were similar in the two groups. Total perioperative drug cost per patient was CAN$38.10+/-10.13 (mean +/- SD) for the sevoflurane group and $23.87+/-6.59 for the isoflurane group (P<0.01). Although the nonvolatile drug cost was comparable between the two groups, the volatile drug cost per patient was $19.40+/-8.80 for sevoflurane and $4.50+/-1.90 for isoflurane (P<0.01). This four-fold sevoflurane-to-isoflurane cost difference was the product of two ratios, both based on the volume of liquid anesthetic: the ratio of consumption, 2.1; and the ratio of institutional price, 2.1. Intraoperative hemodynamic response, time until discharge from the PARR and incidences of postoperative nausea and vomiting did not significantly differ between the two groups.
When used to maintain equipotent balanced general anesthesia for daycare arthroscopic menisectomy, volatile consumption and cost were greater for sevoflurane compared with isoflurane. Nonvolatile perioperative drug cost and recovery times were similar, however, in the two groups.</abstract><cop>Toronto, ON</cop><pub>Canadian Anesthesiologists' Society</pub><pmid>10566918</pmid><doi>10.1007/BF03013193</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0832-610X |
| ispartof | Canadian journal of anaesthesia, 1999-11, Vol.46 (11), p.1008-1013 |
| issn | 0832-610X 1496-8975 |
| language | eng |
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| source | Springer Nature |
| subjects | Adult Aged Anesthesia Anesthesia, Inhalation - economics Anesthetics, Inhalation - pharmacology Anesthetics. Neuromuscular blocking agents Arthroscopy - economics Biological and medical sciences Costs and Cost Analysis Double-Blind Method Female Humans Isoflurane - pharmacology Male Medical sciences Menisci, Tibial - surgery Methyl Ethers - pharmacology Middle Aged Neuropharmacology Pharmacology. Drug treatments Prospective Studies Surgery |
| title | Cost comparison of sevoflurane with isoflurane anesthesia in arthroscopic menisectomy surgery |
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