Loading…
Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)
Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)...
Saved in:
| Published in: | Phytotherapy research 2008-07, Vol.22 (7), p.979-981 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103 |
| container_end_page | 981 |
| container_issue | 7 |
| container_start_page | 979 |
| container_title | Phytotherapy research |
| container_volume | 22 |
| creator | Tomosaka, Hideyuki Chin, Young-Won Salim, Angela A Keller, William J Chai, Heebyung Kinghorn, A. Douglas |
| description | Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)tyramine, cannabisin G and (±)-lyoniresinol. Of these, cannabisin G and (±)-lyoniresinol exhibited antioxidant activity in this bioassay. Furthermore, it was found that cannabisin G showed cytoprotective activity in cultured MCF-7 cells modulated by hydrogen peroxide. Copyright © 2008 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/ptr.2443 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69271756</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69271756</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103</originalsourceid><addsrcrecordid>eNp90l9P1TAYBvDGaOSAJn4C3Q0GLoZv_7eXQBBUREWI3DVd15Hpth7bDTnf3p6cBa70qk3zS98nT4vQKwwHGIC8W47xgDBGn6AFBq1LzCV9ihagOS4ZVjdbaDulnwCgCbDnaAsrqjRTdIE-Hg5jG-7b2g5jYYe6cKsxLGMYvRvbO1-40C_DNNSpaGLoiyMfKx_bVNxN3a1db_Yquz6Kq_0X6Flju-RfzusOun5_cnV8Vp5_Of1wfHheOpYjlhWnnLlaSbDUC6GlEoIwJVxOK63DQjcVB-cceOcUtgzAc8GJ40RXGgPdQW839-aYvyefRtO3yfmus4MPUzJCE4klFxnu_RdipXGOITl_pC6GlKJvzDK2vY0rg8GsKza5YrOuONPX861T1fv6Ec6dZrA7A5uc7ZpoB9emB0eAYwKEZFdu3J-286t_DjRfry7nwbNv0-jvH7yNv4yQVHLz4-LUKHYpPl_cfDLfsn-z8Y0Nxt7mxzLX3wlgmr8BJlQT-hccAKlz</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1891870755</pqid></control><display><type>article</type><title>Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Tomosaka, Hideyuki ; Chin, Young-Won ; Salim, Angela A ; Keller, William J ; Chai, Heebyung ; Kinghorn, A. Douglas</creator><creatorcontrib>Tomosaka, Hideyuki ; Chin, Young-Won ; Salim, Angela A ; Keller, William J ; Chai, Heebyung ; Kinghorn, A. Douglas</creatorcontrib><description>Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)tyramine, cannabisin G and (±)-lyoniresinol. Of these, cannabisin G and (±)-lyoniresinol exhibited antioxidant activity in this bioassay. Furthermore, it was found that cannabisin G showed cytoprotective activity in cultured MCF-7 cells modulated by hydrogen peroxide. Copyright © 2008 John Wiley & Sons, Ltd.</description><identifier>ISSN: 0951-418X</identifier><identifier>EISSN: 1099-1573</identifier><identifier>DOI: 10.1002/ptr.2443</identifier><identifier>PMID: 18389483</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>(±)-lyoniresinol ; Anisoles - analysis ; Anisoles - pharmacology ; antioxidant activity ; Antioxidants - chemistry ; Antioxidants - pharmacology ; barberry ; Berberidaceae ; Berberis - chemistry ; Berberis vulgaris ; Biological and medical sciences ; botanical dietary supplements ; cannabisin G ; Cell Line, Tumor ; Cell Survival - drug effects ; Chemical Fractionation ; Chromatography, High Pressure Liquid ; Coumaric Acids - analysis ; Coumaric Acids - pharmacology ; Cytoprotection ; cytoprotective activity ; Free Radical Scavengers ; General pharmacology ; Humans ; Hydroxyl Radical ; Medical sciences ; Naphthalenes - analysis ; Naphthalenes - pharmacology ; Oxidative Stress - drug effects ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Phenols - analysis ; Phenols - pharmacology ; Phytotherapy ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Plant Roots - chemistry</subject><ispartof>Phytotherapy research, 2008-07, Vol.22 (7), p.979-981</ispartof><rights>Copyright © 2008 John Wiley & Sons, Ltd.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103</citedby><cites>FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20512022$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18389483$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tomosaka, Hideyuki</creatorcontrib><creatorcontrib>Chin, Young-Won</creatorcontrib><creatorcontrib>Salim, Angela A</creatorcontrib><creatorcontrib>Keller, William J</creatorcontrib><creatorcontrib>Chai, Heebyung</creatorcontrib><creatorcontrib>Kinghorn, A. Douglas</creatorcontrib><title>Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)</title><title>Phytotherapy research</title><addtitle>Phytother. Res</addtitle><description>Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)tyramine, cannabisin G and (±)-lyoniresinol. Of these, cannabisin G and (±)-lyoniresinol exhibited antioxidant activity in this bioassay. Furthermore, it was found that cannabisin G showed cytoprotective activity in cultured MCF-7 cells modulated by hydrogen peroxide. Copyright © 2008 John Wiley & Sons, Ltd.</description><subject>(±)-lyoniresinol</subject><subject>Anisoles - analysis</subject><subject>Anisoles - pharmacology</subject><subject>antioxidant activity</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>barberry</subject><subject>Berberidaceae</subject><subject>Berberis - chemistry</subject><subject>Berberis vulgaris</subject><subject>Biological and medical sciences</subject><subject>botanical dietary supplements</subject><subject>cannabisin G</subject><subject>Cell Line, Tumor</subject><subject>Cell Survival - drug effects</subject><subject>Chemical Fractionation</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Coumaric Acids - analysis</subject><subject>Coumaric Acids - pharmacology</subject><subject>Cytoprotection</subject><subject>cytoprotective activity</subject><subject>Free Radical Scavengers</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Hydroxyl Radical</subject><subject>Medical sciences</subject><subject>Naphthalenes - analysis</subject><subject>Naphthalenes - pharmacology</subject><subject>Oxidative Stress - drug effects</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Phenols - analysis</subject><subject>Phenols - pharmacology</subject><subject>Phytotherapy</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Roots - chemistry</subject><issn>0951-418X</issn><issn>1099-1573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp90l9P1TAYBvDGaOSAJn4C3Q0GLoZv_7eXQBBUREWI3DVd15Hpth7bDTnf3p6cBa70qk3zS98nT4vQKwwHGIC8W47xgDBGn6AFBq1LzCV9ihagOS4ZVjdbaDulnwCgCbDnaAsrqjRTdIE-Hg5jG-7b2g5jYYe6cKsxLGMYvRvbO1-40C_DNNSpaGLoiyMfKx_bVNxN3a1db_Yquz6Kq_0X6Flju-RfzusOun5_cnV8Vp5_Of1wfHheOpYjlhWnnLlaSbDUC6GlEoIwJVxOK63DQjcVB-cceOcUtgzAc8GJ40RXGgPdQW839-aYvyefRtO3yfmus4MPUzJCE4klFxnu_RdipXGOITl_pC6GlKJvzDK2vY0rg8GsKza5YrOuONPX861T1fv6Ec6dZrA7A5uc7ZpoB9emB0eAYwKEZFdu3J-286t_DjRfry7nwbNv0-jvH7yNv4yQVHLz4-LUKHYpPl_cfDLfsn-z8Y0Nxt7mxzLX3wlgmr8BJlQT-hccAKlz</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>Tomosaka, Hideyuki</creator><creator>Chin, Young-Won</creator><creator>Salim, Angela A</creator><creator>Keller, William J</creator><creator>Chai, Heebyung</creator><creator>Kinghorn, A. Douglas</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)</title><author>Tomosaka, Hideyuki ; Chin, Young-Won ; Salim, Angela A ; Keller, William J ; Chai, Heebyung ; Kinghorn, A. Douglas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>(±)-lyoniresinol</topic><topic>Anisoles - analysis</topic><topic>Anisoles - pharmacology</topic><topic>antioxidant activity</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>barberry</topic><topic>Berberidaceae</topic><topic>Berberis - chemistry</topic><topic>Berberis vulgaris</topic><topic>Biological and medical sciences</topic><topic>botanical dietary supplements</topic><topic>cannabisin G</topic><topic>Cell Line, Tumor</topic><topic>Cell Survival - drug effects</topic><topic>Chemical Fractionation</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Coumaric Acids - analysis</topic><topic>Coumaric Acids - pharmacology</topic><topic>Cytoprotection</topic><topic>cytoprotective activity</topic><topic>Free Radical Scavengers</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Hydroxyl Radical</topic><topic>Medical sciences</topic><topic>Naphthalenes - analysis</topic><topic>Naphthalenes - pharmacology</topic><topic>Oxidative Stress - drug effects</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Phenols - analysis</topic><topic>Phenols - pharmacology</topic><topic>Phytotherapy</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Roots - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tomosaka, Hideyuki</creatorcontrib><creatorcontrib>Chin, Young-Won</creatorcontrib><creatorcontrib>Salim, Angela A</creatorcontrib><creatorcontrib>Keller, William J</creatorcontrib><creatorcontrib>Chai, Heebyung</creatorcontrib><creatorcontrib>Kinghorn, A. Douglas</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Phytotherapy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tomosaka, Hideyuki</au><au>Chin, Young-Won</au><au>Salim, Angela A</au><au>Keller, William J</au><au>Chai, Heebyung</au><au>Kinghorn, A. Douglas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)</atitle><jtitle>Phytotherapy research</jtitle><addtitle>Phytother. Res</addtitle><date>2008-07</date><risdate>2008</risdate><volume>22</volume><issue>7</issue><spage>979</spage><epage>981</epage><pages>979-981</pages><issn>0951-418X</issn><eissn>1099-1573</eissn><abstract>Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)tyramine, cannabisin G and (±)-lyoniresinol. Of these, cannabisin G and (±)-lyoniresinol exhibited antioxidant activity in this bioassay. Furthermore, it was found that cannabisin G showed cytoprotective activity in cultured MCF-7 cells modulated by hydrogen peroxide. Copyright © 2008 John Wiley & Sons, Ltd.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>18389483</pmid><doi>10.1002/ptr.2443</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0951-418X |
| ispartof | Phytotherapy research, 2008-07, Vol.22 (7), p.979-981 |
| issn | 0951-418X 1099-1573 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69271756 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | (±)-lyoniresinol Anisoles - analysis Anisoles - pharmacology antioxidant activity Antioxidants - chemistry Antioxidants - pharmacology barberry Berberidaceae Berberis - chemistry Berberis vulgaris Biological and medical sciences botanical dietary supplements cannabisin G Cell Line, Tumor Cell Survival - drug effects Chemical Fractionation Chromatography, High Pressure Liquid Coumaric Acids - analysis Coumaric Acids - pharmacology Cytoprotection cytoprotective activity Free Radical Scavengers General pharmacology Humans Hydroxyl Radical Medical sciences Naphthalenes - analysis Naphthalenes - pharmacology Oxidative Stress - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenols - analysis Phenols - pharmacology Phytotherapy Plant Extracts - chemistry Plant Extracts - pharmacology Plant Roots - chemistry |
| title | Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry) |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T10%3A52%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antioxidant%20and%20cytoprotective%20compounds%20from%20Berberis%20vulgaris%20(barberry)&rft.jtitle=Phytotherapy%20research&rft.au=Tomosaka,%20Hideyuki&rft.date=2008-07&rft.volume=22&rft.issue=7&rft.spage=979&rft.epage=981&rft.pages=979-981&rft.issn=0951-418X&rft.eissn=1099-1573&rft_id=info:doi/10.1002/ptr.2443&rft_dat=%3Cproquest_cross%3E69271756%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4443-b5354cd870a3e66978662486c0957ac169fb50ccc0ecc81a400e5652c529b9103%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1891870755&rft_id=info:pmid/18389483&rfr_iscdi=true |