Serum levels of matrix metalloproteinase-3 in relation to the development of radiological damage in patients with early rheumatoid arthritis

Objective. To evaluate the significance of serum matrix metalloproteinase-3 (MMP-3) levels in relation to the development of radiological damage (X-ray damage) in early rheumatoid arthritis (RA). Methods. Serum MMP-3 levels were measured in 46 healthy controls (CTRL), 19 osteoarthritis (OA) and 78 R...

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Bibliographic Details
Published in:Rheumatology (Oxford, England) England), 1999-11, Vol.38 (11), p.1081-1087
Main Authors: Posthumus, M. D., Limburg, P. C., Westra, J., Cats, H. A., Stewart, R. E., van Leeuwen, M. A., van Rijswijk, M. H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Arthritis, Rheumatoid - blood
Arthritis, Rheumatoid - diagnostic imaging
Arthritis, Rheumatoid - enzymology
Biological and medical sciences
Biomarkers
C-Reactive Protein - metabolism
Cohort Studies
Diseases of the osteoarticular system
Early rheumatoid arthritis
Female
Follow-Up Studies
Humans
Inflammatory joint diseases
Male
Matrix Metalloproteinase 3 - blood
Medical sciences
Middle Aged
Prospective Studies
Radiography
Radiological damage
Serum matrix metalloproteinase-3
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Summary:Objective. To evaluate the significance of serum matrix metalloproteinase-3 (MMP-3) levels in relation to the development of radiological damage (X-ray damage) in early rheumatoid arthritis (RA). Methods. Serum MMP-3 levels were measured in 46 healthy controls (CTRL), 19 osteoarthritis (OA) and 78 RA patients with joint symptoms for
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/38.11.1081