Complete radiographic response of primary pulmonary angiosarcomas following gemcitabine and taxotere

Summary A small number of patients with angiosarcoma present each year, even fewer of whom have their primary origin site in the lungs. As such, specific treatments are not well defined for this tumor type. We report that the combination of gemcitabine and docetaxel may be an effective regimen for t...

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Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2008-07, Vol.61 (1), p.131-136
Main Authors: Wilson, Rachel, Glaros, Selina, Brown, Richard K.J, Michael, Claire, Reisman, David
Format: Article
Language:English
Subjects:
Angiosarcoma
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Chemotherapy
Deoxycytidine - administration & dosage
Deoxycytidine - analogs & derivatives
Docetaxel
Gemcitabine
Hemangiosarcoma - drug therapy
Hematology, Oncology and Palliative Medicine
Humans
Lung Neoplasms - drug therapy
Male
Medical sciences
Middle Aged
PET scan
Pneumology
Positron-Emission Tomography
Pulmonary/Respiratory
Radiological response
Taxoids - administration & dosage
Tomography, X-Ray Computed
Tumors
Tumors of the respiratory system and mediastinum
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Summary:Summary A small number of patients with angiosarcoma present each year, even fewer of whom have their primary origin site in the lungs. As such, specific treatments are not well defined for this tumor type. We report that the combination of gemcitabine and docetaxel may be an effective regimen for the treatment of angiosarcoma, as illustrated by the complete radiological response observed. In this case report, we review the clinical characteristics, prevalence and treatment options for angiosarcoma. In particular, we review the potential pitfalls and important attributes that should inform diagnosis.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2007.12.006