Dietary sodium, an independent determinant for urinary deoxypyridinoline in elderly women. A cross-sectional study on the effect of dietary factors on deoxypyridinoline excretion in 24-h urine specimens from 763 free-living healthy Japanese

• Published in: European journal of clinical nutrition 1999-11, Vol.53 (11), p.886-890
• Main Authors: ITOH, R, SUYAMA, Y, OGUMA, Y, YOKOTA, F
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aging; Amino Acids - urine; Analysis of Variance; Biological and medical sciences; Bone loss; Bone resorption; Bone Resorption - urine; Calcium; Calcium (urinary); Calcium - urine; Calcium, Dietary - administration & dosage; Creatinine; Creatinine - urine; Cross-Sectional Studies; Deoxypyridinoline; Diet; Dietary Proteins - administration & dosage; Diseases of the osteoarticular system; Excretion; Female; Humans; Japan; Local government; Male; Medical sciences; Middle Aged; Multiple regression models; Nutrition; Older people; Osteoporosis. Osteomalacia. Paget disease; Proteins; Sodium; Sodium - urine; Sodium, Dietary - administration & dosage; Urea; Urea - urine; Urine
• ISSN: 0954-3007; 1476-5640
• DOI: 10.1038/sj.ejcn.1600871

To investigate the effect of sodium, protein and calcium in habitual diets on bone resorption. A cross-sectional study. A community-based study. Healthy free-living male (n=342) and female (n=421) volunteers aged 20-79 y recruited for a health and nutrition examination survey conducted by a local government. Bone resorption was assessed by the measurement of free deoxypyridinoline in 24 h urine. Dietary assessment was by one-day dietary record method. Sodium and urea in 24 h urine were also measured for assessment of sodium and protein intake. The relationships between deoxypyridinoline excretion and the dietary factors were examined using correlation and multiple regression statistics. In women aged 50-79 y, protein intake was positively associated with deoxypyridinoline excretion (P