Multiple drug resistance

Multiple drug resistance to antibacterial agents, antifungals, antivirals, antiprotozoals, and antitumor agents has risen spectacularly in the last decade or so and presently threatens eventually to put an end to successful chemotherapy in all of the above fields. This review summarizes the known or...

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Bibliographic Details
Published in:Medicinal research reviews 1999-11, Vol.19 (6), p.477-496
Main Authors: Mitscher, Lester A., Pillai, Segaran P., Gentry, Elmer J., Shankel, Delbert M.
Format: Article
Language:English
Subjects:
Animals
Anti-Infective Agents - chemistry
Anti-Infective Agents - therapeutic use
Applied microbiology
Biological and medical sciences
Drug Resistance, Multiple
Fundamental and applied biological sciences. Psychology
Humans
Microbiology
Miscellaneous
multiple drug resistance
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Summary:Multiple drug resistance to antibacterial agents, antifungals, antivirals, antiprotozoals, and antitumor agents has risen spectacularly in the last decade or so and presently threatens eventually to put an end to successful chemotherapy in all of the above fields. This review summarizes the known origins of the problem, its present dimensions, the means employed to combat the phenomenon and promising avenues for future developments. © 1999 John Wiley & Sons, Inc. Med Res Rev, 19, No. 6, 477–496, 1999
ISSN:0198-6325
1098-1128
DOI:10.1002/(SICI)1098-1128(199911)19:6<477::AID-MED2>3.0.CO;2-W