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NOVEL SURGICAL MANAGEMENT OF RENAL TRAUMA: INLINE RADIOFREQUENCY ABLATION COAGULATION
Background: Renal injury accounts for 10% of all abdominal trauma. Low‐grade renal injuries can be managed without surgery. However, patients with grade IV or grade V injuries may require nephrectomy. In this study, InLine radiofrequency ablation device (ILRFA), which we developed for liver surgery...
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Published in: | ANZ journal of surgery 2008-07, Vol.78 (7), p.601-604 |
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container_title | ANZ journal of surgery |
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creator | Yao, Peng Gunasegaram, Aravin Ladd, Leigh A. Morris, David L. |
description | Background: Renal injury accounts for 10% of all abdominal trauma. Low‐grade renal injuries can be managed without surgery. However, patients with grade IV or grade V injuries may require nephrectomy. In this study, InLine radiofrequency ablation device (ILRFA), which we developed for liver surgery was tested in the animal model of simulated renal injury.
Methods: A grade IV renal injury was induced in eight landrace pigs. Then treatment with ILRFA was compared to conventional diathermy and suture; totally 24 surgeries were carried out (12 ILRFA vs 12 control).
Results: No massive bleeding occurred and no animal died during the experiments. Immediately after surgery, the pigs were given euthanasia. The average of RFA coagulation time was 3.5 min. The mean intraoperative blood loss was 42 ± 16 mL in the ILRFA and 195 ± 58 mL in the control, a 78.5% reduction (P |
doi_str_mv | 10.1111/j.1445-2197.2008.04583.x |
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Methods: A grade IV renal injury was induced in eight landrace pigs. Then treatment with ILRFA was compared to conventional diathermy and suture; totally 24 surgeries were carried out (12 ILRFA vs 12 control).
Results: No massive bleeding occurred and no animal died during the experiments. Immediately after surgery, the pigs were given euthanasia. The average of RFA coagulation time was 3.5 min. The mean intraoperative blood loss was 42 ± 16 mL in the ILRFA and 195 ± 58 mL in the control, a 78.5% reduction (P < 0.001). The mean blood loss per centimetre squared of resection area was 4.50 ± 2.84 mL/cm2 in the ILRFA compared with 18.73 ± 6.89 mL/cm2 in controls, the reduction was 76.0% (P = 0.001).
Conclusion: InLine RFA is efficient for the management of haemorrhage in renal trauma in an animal model and deserves clinical evaluation.</description><identifier>ISSN: 1445-1433</identifier><identifier>EISSN: 1445-2197</identifier><identifier>DOI: 10.1111/j.1445-2197.2008.04583.x</identifier><identifier>PMID: 18593419</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>Animals ; bipolar InLine radiofrequency ablation device ; blood loss ; Catheter Ablation ; Hemorrhage ; Hogs ; Injuries ; Kidney - injuries ; Kidney - surgery ; Kidneys ; Medical technology ; radiofrequency ablation ; renal trauma ; Surgery</subject><ispartof>ANZ journal of surgery, 2008-07, Vol.78 (7), p.601-604</ispartof><rights>2008 The Authors Journal compilation © 2008 Royal Australasian College of Surgeons</rights><rights>Journal compilation © 2008 Royal Australasian College of Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4323-49979a9eb4f072cc264441b39291e5cfd0bc6870652c2be00615f7e04b8be8123</citedby><cites>FETCH-LOGICAL-c4323-49979a9eb4f072cc264441b39291e5cfd0bc6870652c2be00615f7e04b8be8123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18593419$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yao, Peng</creatorcontrib><creatorcontrib>Gunasegaram, Aravin</creatorcontrib><creatorcontrib>Ladd, Leigh A.</creatorcontrib><creatorcontrib>Morris, David L.</creatorcontrib><title>NOVEL SURGICAL MANAGEMENT OF RENAL TRAUMA: INLINE RADIOFREQUENCY ABLATION COAGULATION</title><title>ANZ journal of surgery</title><addtitle>ANZ J Surg</addtitle><description>Background: Renal injury accounts for 10% of all abdominal trauma. Low‐grade renal injuries can be managed without surgery. However, patients with grade IV or grade V injuries may require nephrectomy. In this study, InLine radiofrequency ablation device (ILRFA), which we developed for liver surgery was tested in the animal model of simulated renal injury.
Methods: A grade IV renal injury was induced in eight landrace pigs. Then treatment with ILRFA was compared to conventional diathermy and suture; totally 24 surgeries were carried out (12 ILRFA vs 12 control).
Results: No massive bleeding occurred and no animal died during the experiments. Immediately after surgery, the pigs were given euthanasia. The average of RFA coagulation time was 3.5 min. The mean intraoperative blood loss was 42 ± 16 mL in the ILRFA and 195 ± 58 mL in the control, a 78.5% reduction (P < 0.001). The mean blood loss per centimetre squared of resection area was 4.50 ± 2.84 mL/cm2 in the ILRFA compared with 18.73 ± 6.89 mL/cm2 in controls, the reduction was 76.0% (P = 0.001).
Conclusion: InLine RFA is efficient for the management of haemorrhage in renal trauma in an animal model and deserves clinical evaluation.</description><subject>Animals</subject><subject>bipolar InLine radiofrequency ablation device</subject><subject>blood loss</subject><subject>Catheter Ablation</subject><subject>Hemorrhage</subject><subject>Hogs</subject><subject>Injuries</subject><subject>Kidney - injuries</subject><subject>Kidney - surgery</subject><subject>Kidneys</subject><subject>Medical technology</subject><subject>radiofrequency ablation</subject><subject>renal trauma</subject><subject>Surgery</subject><issn>1445-1433</issn><issn>1445-2197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqNkF1r2zAUhsVoWbtuf2GIXvTOrr4sS4VdaJmTGhyZOXbHrg62K0OypOmshqX_fk4dWtjVdKOD9LznHB6EMCUhHc71KqRCRAGjOg4ZISokIlI83L9D568fJ8eaCs7P0AfvV4RQKXX0Hp1RFWkuqD5Hlc3vkgwvqmKWTkyG58aaWTJPbInzKS4SO7yVhanm5ganNkttggvzLc2nRfK9SuzkJzZfM1OmucWT3Myqsf6ITrt67d2n432BqmlSTm6DLH8ZE7SCMx4IrWNda9eIjsSsbZkUQtCGa6api9runjStVDGREWtZ4wiRNOpiR0SjGqco4xfoauz72G9_75x_gs3St269rh_cdudBaqa41HoAL_8BV9td_zDsBlQrJtmgb4DUCLX91vvedfDYLzd1_wyUwME7rOCgFA564eAdXrzDfoh-PvbfNRt3_xY8ih6ALyPwZ7l2z__dGIxdiHG3YMwv_ZPbv-br_hfImMcR_LAzWBQlueOCQMz_AszUlqI</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>Yao, Peng</creator><creator>Gunasegaram, Aravin</creator><creator>Ladd, Leigh A.</creator><creator>Morris, David L.</creator><general>Blackwell Publishing Asia</general><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>NOVEL SURGICAL MANAGEMENT OF RENAL TRAUMA: INLINE RADIOFREQUENCY ABLATION COAGULATION</title><author>Yao, Peng ; Gunasegaram, Aravin ; Ladd, Leigh A. ; Morris, David L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4323-49979a9eb4f072cc264441b39291e5cfd0bc6870652c2be00615f7e04b8be8123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>bipolar InLine radiofrequency ablation device</topic><topic>blood loss</topic><topic>Catheter Ablation</topic><topic>Hemorrhage</topic><topic>Hogs</topic><topic>Injuries</topic><topic>Kidney - injuries</topic><topic>Kidney - surgery</topic><topic>Kidneys</topic><topic>Medical technology</topic><topic>radiofrequency ablation</topic><topic>renal trauma</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yao, Peng</creatorcontrib><creatorcontrib>Gunasegaram, Aravin</creatorcontrib><creatorcontrib>Ladd, Leigh A.</creatorcontrib><creatorcontrib>Morris, David L.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>ANZ journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yao, Peng</au><au>Gunasegaram, Aravin</au><au>Ladd, Leigh A.</au><au>Morris, David L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NOVEL SURGICAL MANAGEMENT OF RENAL TRAUMA: INLINE RADIOFREQUENCY ABLATION COAGULATION</atitle><jtitle>ANZ journal of surgery</jtitle><addtitle>ANZ J Surg</addtitle><date>2008-07</date><risdate>2008</risdate><volume>78</volume><issue>7</issue><spage>601</spage><epage>604</epage><pages>601-604</pages><issn>1445-1433</issn><eissn>1445-2197</eissn><abstract>Background: Renal injury accounts for 10% of all abdominal trauma. Low‐grade renal injuries can be managed without surgery. However, patients with grade IV or grade V injuries may require nephrectomy. In this study, InLine radiofrequency ablation device (ILRFA), which we developed for liver surgery was tested in the animal model of simulated renal injury.
Methods: A grade IV renal injury was induced in eight landrace pigs. Then treatment with ILRFA was compared to conventional diathermy and suture; totally 24 surgeries were carried out (12 ILRFA vs 12 control).
Results: No massive bleeding occurred and no animal died during the experiments. Immediately after surgery, the pigs were given euthanasia. The average of RFA coagulation time was 3.5 min. The mean intraoperative blood loss was 42 ± 16 mL in the ILRFA and 195 ± 58 mL in the control, a 78.5% reduction (P < 0.001). The mean blood loss per centimetre squared of resection area was 4.50 ± 2.84 mL/cm2 in the ILRFA compared with 18.73 ± 6.89 mL/cm2 in controls, the reduction was 76.0% (P = 0.001).
Conclusion: InLine RFA is efficient for the management of haemorrhage in renal trauma in an animal model and deserves clinical evaluation.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>18593419</pmid><doi>10.1111/j.1445-2197.2008.04583.x</doi><tpages>4</tpages></addata></record> |
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subjects | Animals bipolar InLine radiofrequency ablation device blood loss Catheter Ablation Hemorrhage Hogs Injuries Kidney - injuries Kidney - surgery Kidneys Medical technology radiofrequency ablation renal trauma Surgery |
title | NOVEL SURGICAL MANAGEMENT OF RENAL TRAUMA: INLINE RADIOFREQUENCY ABLATION COAGULATION |
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