Glutathione and its role in cellular functions

Glutathione (GSH) is the major cellular thiol participating in cellular redox reactions and thioether formation. This article serves as introduction to the FRBM Forum on glutathione and emphasizes cellular functions: What is GSH? Where does it come from? Where does it go? What does it do? What is ne...

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Bibliographic Details
Published in:Free radical biology & medicine 1999-11, Vol.27 (9), p.916-921
Main Author: Sies, Helmut
Format: Article
Language:English
Subjects:
Animals
Apoptosis
Free radicals
Free Radicals - metabolism
Gene expression
Glutathione
Glutathione - history
Glutathione - metabolism
Glutathione conjugation
Glutathionylation
History of medicine
History, 19th Century
History, 20th Century
Humans
Oxidation-Reduction
Redox state
Subcellular compartmentation
Thiols
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Summary:Glutathione (GSH) is the major cellular thiol participating in cellular redox reactions and thioether formation. This article serves as introduction to the FRBM Forum on glutathione and emphasizes cellular functions: What is GSH? Where does it come from? Where does it go? What does it do? What is new and noteworthy? Research tools, historical remarks, and links to current trends.
ISSN:0891-5849
1873-4596
DOI:10.1016/S0891-5849(99)00177-X