Yolk sac tumor in the nasal cavity

Abstract Yolk sac carcinoma (YST) is rare malignant tumor of germ cell origin. It most commonly arises from the gonads but extragonadal sites of origin are reported in 20% of the cases. Head and neck germ cell tumors are uncommon and only a small number are malignant. We present the case of a 48 yea...

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Bibliographic Details
Published in:American journal of otolaryngology 2008-07, Vol.29 (4), p.250-254
Main Authors: Filho, Bernardo Cunha Araujo, MD, McHugh, Jonathan B, Carrau, Ricardo L., MD, Kassam, Amin B., MD
Format: Article
Language:English
Subjects:
Abdomen
Biological and medical sciences
Cancer
Chemotherapy
Endodermal Sinus Tumor - diagnostic imaging
Endodermal Sinus Tumor - pathology
Endodermal Sinus Tumor - surgery
Female
Humans
Male
Medical imaging
Medical sciences
Middle Aged
Nasal Cavity
Nose
Nose Neoplasms - diagnostic imaging
Nose Neoplasms - pathology
Nose Neoplasms - surgery
Otolaryngology
Otorhinolaryngology. Stomatology
Radiation therapy
Sinuses
Surgery
Tomography
Tomography, X-Ray Computed
Tumors
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Summary:Abstract Yolk sac carcinoma (YST) is rare malignant tumor of germ cell origin. It most commonly arises from the gonads but extragonadal sites of origin are reported in 20% of the cases. Head and neck germ cell tumors are uncommon and only a small number are malignant. We present the case of a 48 years old man presenting with a YST of the sinonasal tract and the arterior skull base. The patient underwent an anterior craniofacial resection and postoperative radiotherapy and continues showing no evidence of disease seven years after treatment. We discuss radiological and histological features of this tumor and provide a review of three other cases of YST arising in children.
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2007.09.001