Tunneled Right Atrial Catheter Infection Presenting as Renal Failure

We report two cases of progressive renal failure secondary to membranoproliferative glomerulonephritis associated with subclinical septicemia from a tunneled right atrial catheter used for home parenteral nutrition administration. Although the occurrence of line infection and septicemia is a common...

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Bibliographic Details
Published in:JPEN. Journal of parenteral and enteral nutrition 1999-11, Vol.23 (6), p.363-365
Main Authors: Yared, George, Seidner, Douglas L., Steiger, Ezra, Hall, Phillip M., Nally, Joseph V.
Format: Article
Language:English
Subjects:
Aged
Catheterization, Central Venous - adverse effects
Glomerulonephritis, Membranoproliferative - etiology
Humans
Male
Middle Aged
Parenteral Nutrition, Home - adverse effects
Renal Insufficiency - etiology
Sepsis - etiology
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Summary:We report two cases of progressive renal failure secondary to membranoproliferative glomerulonephritis associated with subclinical septicemia from a tunneled right atrial catheter used for home parenteral nutrition administration. Although the occurrence of line infection and septicemia is a common complication of central venous catheters, a review of the literature reveals only one case report of renal failure secondary to an infected implanted central venous device. Both patients presented with azotemia and had biopsy-proven membranoproliferative glomerulonephritis, accompanied by leukocytoclastic vasculitis. In both cases, removal of the right atrial catheter and prolonged antibiotic therapy was effective in resolving the ongoing infection and resulted in marked improvement in renal function. A high index of suspicion for catheter sepsis should be maintained in patients with tunneled right atrial catheters presenting with subacute renal failure. (Journal of Parenteral and Enteral Nutrition 23:363-365, 1999)
ISSN:0148-6071
1941-2444
DOI:10.1177/0148607199023006363