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Distinctive Neurobehavioral Features Among Neurodegenerative Dementias
The distinctive neuropsychiatric features of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) were investigated by using the Neuropsychiatric Inventory. The patients with FTD had significantly more euphoria, aberrant motor activity, and disinhibition...
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Published in: | The journal of neuropsychiatry and clinical neurosciences 1999-11, Vol.11 (4), p.498-503 |
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container_title | The journal of neuropsychiatry and clinical neurosciences |
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creator | Hirono, Nobutsugu Mori, Etsuro Tanimukai, Satoshi Kazui, Hiroaki Hashimoto, Mamoru Hanihara, Tokiji Imamura, Toru |
description | The distinctive neuropsychiatric features of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) were investigated by using the Neuropsychiatric Inventory. The patients with FTD had significantly more euphoria, aberrant motor activity, and disinhibition and significantly fewer delusions compared with the patients with AD or DLB. The patients with DLB had significantly more hallucinations compared with the AD or FTD patients. The findings clearly demonstrate that AD, DLB, and FTD have distinctive neuropsychiatric features, which may correspond to different patterns of cerebral involvement characteristic of these three major degenerative dementias. |
doi_str_mv | 10.1176/jnp.11.4.498 |
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The patients with FTD had significantly more euphoria, aberrant motor activity, and disinhibition and significantly fewer delusions compared with the patients with AD or DLB. The patients with DLB had significantly more hallucinations compared with the AD or FTD patients. The findings clearly demonstrate that AD, DLB, and FTD have distinctive neuropsychiatric features, which may correspond to different patterns of cerebral involvement characteristic of these three major degenerative dementias.</description><identifier>ISSN: 0895-0172</identifier><identifier>EISSN: 1545-7222</identifier><identifier>DOI: 10.1176/jnp.11.4.498</identifier><identifier>PMID: 10570764</identifier><identifier>CODEN: JNCNE7</identifier><language>eng</language><publisher>United States: American Psychiatric Publishing</publisher><subject>Aged ; Atrophy - pathology ; Dementia - etiology ; Dementia - psychology ; Female ; Frontal Lobe - pathology ; Hallucinations - diagnosis ; Hallucinations - etiology ; Humans ; Male ; Neurodegenerative Diseases - complications ; Neurodegenerative Diseases - pathology ; Psychomotor Disorders - diagnosis ; Psychomotor Disorders - etiology ; Sensitivity and Specificity ; Severity of Illness Index ; Temporal Lobe - pathology</subject><ispartof>The journal of neuropsychiatry and clinical neurosciences, 1999-11, Vol.11 (4), p.498-503</ispartof><rights>Copyright American Psychiatric Press, Inc. 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The findings clearly demonstrate that AD, DLB, and FTD have distinctive neuropsychiatric features, which may correspond to different patterns of cerebral involvement characteristic of these three major degenerative dementias.</description><subject>Aged</subject><subject>Atrophy - pathology</subject><subject>Dementia - etiology</subject><subject>Dementia - psychology</subject><subject>Female</subject><subject>Frontal Lobe - pathology</subject><subject>Hallucinations - diagnosis</subject><subject>Hallucinations - etiology</subject><subject>Humans</subject><subject>Male</subject><subject>Neurodegenerative Diseases - complications</subject><subject>Neurodegenerative Diseases - pathology</subject><subject>Psychomotor Disorders - diagnosis</subject><subject>Psychomotor Disorders - etiology</subject><subject>Sensitivity and Specificity</subject><subject>Severity of Illness Index</subject><subject>Temporal Lobe - pathology</subject><issn>0895-0172</issn><issn>1545-7222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNptkM1Lw0AQxRdRbK3ePEvxIAim7m422eyxtFaFohc9L7PJpKbky92k4H_vanoo4mGYB_ObN8Mj5JLRGWMyvt_WrRczMRMqOSJjFokokJzzYzKmiYoCyiQfkTPntpRSHsbilIwYjSSVsRiT1bJwXVGnXbHD6Qv2tjH4AbuisVBOVwhdb9FN51VTb4Zxhhus0cLvwhIrrLsC3Dk5yaF0eLHvE_K-enhbPAXr18fnxXwdQChZFwgJMU-4QsGVMSaHLIWc0oiHxlCVxoarNEohlio0ivnCDPLQyBggzzDPwwm5GXxb23z26DpdFS7FsoQam97pWHEVqUR68PoPuG16W_vfNFMRF0okzEN3A5TaxjmLuW5tUYH90ozqn3C1D9cLLbQP1-NXe8_eVJgdwEOaHrgdAGjb4uDgf2bfQuiEKA</recordid><startdate>199911</startdate><enddate>199911</enddate><creator>Hirono, Nobutsugu</creator><creator>Mori, Etsuro</creator><creator>Tanimukai, Satoshi</creator><creator>Kazui, Hiroaki</creator><creator>Hashimoto, Mamoru</creator><creator>Hanihara, Tokiji</creator><creator>Imamura, Toru</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Publishing, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>199911</creationdate><title>Distinctive Neurobehavioral Features Among Neurodegenerative Dementias</title><author>Hirono, Nobutsugu ; 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The patients with FTD had significantly more euphoria, aberrant motor activity, and disinhibition and significantly fewer delusions compared with the patients with AD or DLB. The patients with DLB had significantly more hallucinations compared with the AD or FTD patients. The findings clearly demonstrate that AD, DLB, and FTD have distinctive neuropsychiatric features, which may correspond to different patterns of cerebral involvement characteristic of these three major degenerative dementias.</abstract><cop>United States</cop><pub>American Psychiatric Publishing</pub><pmid>10570764</pmid><doi>10.1176/jnp.11.4.498</doi><tpages>6</tpages></addata></record> |
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subjects | Aged Atrophy - pathology Dementia - etiology Dementia - psychology Female Frontal Lobe - pathology Hallucinations - diagnosis Hallucinations - etiology Humans Male Neurodegenerative Diseases - complications Neurodegenerative Diseases - pathology Psychomotor Disorders - diagnosis Psychomotor Disorders - etiology Sensitivity and Specificity Severity of Illness Index Temporal Lobe - pathology |
title | Distinctive Neurobehavioral Features Among Neurodegenerative Dementias |
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