Lipidemic effects of an interesterified mixture of butter, medium-chain triacylglycerol and safflower oils

The objective of this study was to determine if the positional structure of dietary triacylglycerol affected lipidemic responses. Thirty healthy adults (16 men and 14 postmenopausal women) with low‐density lipoprotein cholesterol (LDL‐C) concentrations >3.37 mM (130 mg/dl) enrolled in a prospecti...

Full description

Saved in:
Bibliographic Details
Published in:Lipids 1999-09, Vol.34 (9), p.889-894
Main Authors: Mascioli, E.A, McLennan, C.E, Schaefer, E.J, Lichtenstein, A.H, Hoy, C.E, Christensen, M.S, Bistrian, B.R
Format: Article
Language:English
Subjects:
Adipose Tissue
Aged
Alcohol Drinking
Body Composition
Butter
cholesteremic effect
Cholesterol
cholesterol metabolism
clinical trials
Cross-Over Studies
Diet
dietary fat
Dietary Fats - administration & dosage
Dietary Fats - pharmacology
Double-Blind Method
Esterification
Fatty Acids - administration & dosage
Fatty Acids - chemistry
Female
Humans
Hypercholesterolemia - blood
interesterification
Lipids - blood
Low density lipoprotein
Male
medium chain triacylglycerols
men
Middle Aged
Obesity - blood
Postmenopause
Safflower oil
Safflower Oil - administration & dosage
Triglycerides - administration & dosage
Triglycerides - chemistry
Vegetable oils
women
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this study was to determine if the positional structure of dietary triacylglycerol affected lipidemic responses. Thirty healthy adults (16 men and 14 postmenopausal women) with low‐density lipoprotein cholesterol (LDL‐C) concentrations >3.37 mM (130 mg/dl) enrolled in a prospective, single‐blind, cross‐over outpatient clinical trial that consisted of two 5‐wk dietary phases. After baseline screening, subjects were instructed to follow individualized meal plans (weight maintenance diets with 36% of total energy from fat, half of which was from a test oil) and randomized to receive either butter (B) or an interesterified mixture (IM) of butter, medium‐chain triacylglycerol (MCI), and safflower oils. Blood drawn during weeks 5 and 10 of feeding was analyzed for total cholesterol (TC), high density lipoprotein cholesterol (HDL‐C), LDL‐C, and triacylglycerols (TAG). Mean plasma levels of TC (B, 6.98±1.06 mM; IM, 7.09±1.20 mM), HDL‐C (B,1.30±0.35 mM; IM, 1.29±0.34 mM), and LDL‐C (B, 4.91±0.95 mM; IM, 492±1.10 mM) were not significantly different between the two dietary treatments. Mean TAG levels were higher for the interesterified B‐MCT mixture (B, 1.75±0.72 mM; IM, 1.96±0.86 mM, P
ISSN:0024-4201
1558-9307
DOI:10.1007/s11745-999-0437-x