Surgical treatment of primary hyperparathyroidism in children: Report of 10 cases

Summary Primary hyperparathyroidism in children is very rare. It is caused by overproduction of parathormone by a pathologically changed parathyroid gland. We carried out a retrospective study in 10 patients (age 10–17 years) who had surgical treatment between 1996 and 2007. The main signs of primar...

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Published in:International journal of pediatric otorhinolaryngology 2008-08, Vol.72 (8), p.1177-1182
Main Authors: Libánský, Petr, Astl, Jaromír, Adámek, Svatopluk, Naňka, Ondřej, Pafko, Pavel, Špačková, Jana, Foltán, René, Šedý, Jiří
Format: Article
Language:English
Subjects:
Adolescent
Biomarkers - blood
Calcium - blood
Child
Female
Humans
Hyperparathyroidism, Primary - blood
Hyperparathyroidism, Primary - surgery
Male
Otolaryngology
Parathyroid adenoma
Parathyroid Hormone - blood
Parathyroidectomy
Pediatrics
Primary hyperparathyroidism
Treatment Outcome
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Summary:Summary Primary hyperparathyroidism in children is very rare. It is caused by overproduction of parathormone by a pathologically changed parathyroid gland. We carried out a retrospective study in 10 patients (age 10–17 years) who had surgical treatment between 1996 and 2007. The main signs of primary hyperparathyroidism were urolithiasis, nephrolithiasis, nephrocalcinosis and bone resorption, as well as non-specific signs such as fatigue, torpidness and muscle weakness. Patients were examined using sonography, MIBI-scintigraphy, CT and MRI. Calcium was measured before and after surgery; parathormone was monitored postoperatively. Surgery was curative in nine patients; reoperation was necessary in one patient because an ectopic parathyroid gland was not detected during the primary operation. Other major complications were not observed. Removal of pathologically changed parathyroid glands offers definitive and safe treatment of primary hyperparathyroidism in children. Special care should be taken if an ectopic parathyroid gland is suspected.
ISSN:0165-5876
1872-8464
DOI:10.1016/j.ijporl.2008.04.005