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Nocardiosis in Adult-Onset Still’s Disease and Vasculitis Syndrome
Four cases of nocardiosis in patients with adult-onset Still disease and vasculitis syndrome are presented. Three patients developed lung abscesses and 1 case developed a brain abscess. All were treated with high-dose corticosteroids, and 3 were given cyclosporine when they developed nocardiosis. Al...
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Published in: | The American journal of the medical sciences 2008-07, Vol.336 (1), p.77-80 |
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container_title | The American journal of the medical sciences |
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creator | Tada, Yoshifumi Mitamura, Mio Koarada, Shuichi Suematsu, Rie Inoue, Hisako Nagasawa, Kohei Fukuoka, Mami Ohta, Akihide |
description | Four cases of nocardiosis in patients with adult-onset Still disease and vasculitis syndrome are presented. Three patients developed lung abscesses and 1 case developed a brain abscess. All were treated with high-dose corticosteroids, and 3 were given cyclosporine when they developed nocardiosis. All patients were successfully treated with antibiotics; cyclosporine was discontinued in 2 cases. These cases indicate that systemic nocardiosis can develop in patients with various rheumatologic diseases who are treated with corticosteroid and immunosuppressive drugs such as cyclosporine. |
doi_str_mv | 10.1097/MAJ.0b013e318159e0b4 |
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Three patients developed lung abscesses and 1 case developed a brain abscess. All were treated with high-dose corticosteroids, and 3 were given cyclosporine when they developed nocardiosis. All patients were successfully treated with antibiotics; cyclosporine was discontinued in 2 cases. 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Mitamura, Mio ; Koarada, Shuichi ; Suematsu, Rie ; Inoue, Hisako ; Nagasawa, Kohei ; Fukuoka, Mami ; Ohta, Akihide</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456t-9ae943d3b20d048d280cb80aa09187248257e7a770cda66e9c22432aa3aacfc93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adrenal Cortex Hormones - administration & dosage</topic><topic>Adult</topic><topic>Adult-onset Still’s disease</topic><topic>Aged</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Brain Abscess - complications</topic><topic>Brain Abscess - diagnostic imaging</topic><topic>Brain Abscess - drug therapy</topic><topic>Cyclosporine</topic><topic>Cyclosporine - administration & dosage</topic><topic>Female</topic><topic>General aspects</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Lung Abscess - complications</topic><topic>Lung Abscess - diagnostic imaging</topic><topic>Lung Abscess - drug therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Nocardia Infections - complications</topic><topic>Nocardiosis</topic><topic>Still's Disease, Adult-Onset - complications</topic><topic>Tomography, X-Ray Computed</topic><topic>Vasculitis</topic><topic>Vasculitis - complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tada, Yoshifumi</creatorcontrib><creatorcontrib>Mitamura, Mio</creatorcontrib><creatorcontrib>Koarada, Shuichi</creatorcontrib><creatorcontrib>Suematsu, Rie</creatorcontrib><creatorcontrib>Inoue, Hisako</creatorcontrib><creatorcontrib>Nagasawa, Kohei</creatorcontrib><creatorcontrib>Fukuoka, Mami</creatorcontrib><creatorcontrib>Ohta, Akihide</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of the medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tada, Yoshifumi</au><au>Mitamura, Mio</au><au>Koarada, Shuichi</au><au>Suematsu, Rie</au><au>Inoue, Hisako</au><au>Nagasawa, Kohei</au><au>Fukuoka, Mami</au><au>Ohta, Akihide</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nocardiosis in Adult-Onset Still’s Disease and Vasculitis Syndrome</atitle><jtitle>The American journal of the medical sciences</jtitle><addtitle>Am J Med Sci</addtitle><date>2008-07-01</date><risdate>2008</risdate><volume>336</volume><issue>1</issue><spage>77</spage><epage>80</epage><pages>77-80</pages><issn>0002-9629</issn><eissn>1538-2990</eissn><coden>AJMSA9</coden><abstract>Four cases of nocardiosis in patients with adult-onset Still disease and vasculitis syndrome are presented. Three patients developed lung abscesses and 1 case developed a brain abscess. All were treated with high-dose corticosteroids, and 3 were given cyclosporine when they developed nocardiosis. All patients were successfully treated with antibiotics; cyclosporine was discontinued in 2 cases. These cases indicate that systemic nocardiosis can develop in patients with various rheumatologic diseases who are treated with corticosteroid and immunosuppressive drugs such as cyclosporine.</abstract><cop>Hagerstown, MD</cop><pub>Elsevier Inc</pub><pmid>18626243</pmid><doi>10.1097/MAJ.0b013e318159e0b4</doi><tpages>4</tpages></addata></record> |
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subjects | Adrenal Cortex Hormones - administration & dosage Adult Adult-onset Still’s disease Aged Bacterial diseases Biological and medical sciences Brain Abscess - complications Brain Abscess - diagnostic imaging Brain Abscess - drug therapy Cyclosporine Cyclosporine - administration & dosage Female General aspects Human bacterial diseases Humans Infectious diseases Lung Abscess - complications Lung Abscess - diagnostic imaging Lung Abscess - drug therapy Male Medical sciences Miscellaneous Nocardia Infections - complications Nocardiosis Still's Disease, Adult-Onset - complications Tomography, X-Ray Computed Vasculitis Vasculitis - complications |
title | Nocardiosis in Adult-Onset Still’s Disease and Vasculitis Syndrome |
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