Solitary Bone Plasmacytoma: Management of Isolated Local Relapse Following Radiotherapy

Radiotherapy is the prime treatment modality for solitary plasmacytomas of bone (SPB). Although local control rates are excellent, progression to multiple myeloma is frequent, albeit with varying latency. Local failure in the absence of dissemination is rare and thus management is poorly documented....

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Bibliographic Details
Published in:Clinical oncology (Royal College of Radiologists (Great Britain)) 1999-01, Vol.11 (5), p.348-351
Main Authors: Lewanski, C.R., Bates, T., Bowen, J., Ashford, R.F.U.
Format: Article
Language:English
Subjects:
Acetabulum - diagnostic imaging
Acetabulum - surgery
Biological and medical sciences
Bone
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - radiotherapy
Bone Neoplasms - surgery
Disease Progression
Hematologic and hematopoietic diseases
Hemopathies
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Local recurrence
Male
Medical sciences
Middle Aged
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - surgery
Plasmacytoma
Plasmacytoma - diagnostic imaging
Plasmacytoma - radiotherapy
Plasmacytoma - surgery
Pubic Bone - diagnostic imaging
Pubic Bone - surgery
Radiography
Radiotherapy
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Surgery
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Summary:Radiotherapy is the prime treatment modality for solitary plasmacytomas of bone (SPB). Although local control rates are excellent, progression to multiple myeloma is frequent, albeit with varying latency. Local failure in the absence of dissemination is rare and thus management is poorly documented. We discuss such a patient who presented 3 years after local radiation for a pelvic SPB and review the relevant literature. Radiation doses, portals employed and prognostic factors that may predict progression to myeloma are discussed. This report shows that an isolated recurrence of SPB in a previously irradiated field was successfully treated with orthopaedic surgery. This resulted in good pain relief and mobility for the patient, who remains free of disease 6 months after operation.
ISSN:0936-6555
1433-2981
DOI:10.1053/clon.1999.9078