Clinical management of six cases of low-risk primary tonsillar non-Hodgkin's lymphoma

There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. We report six cases of primary tonsillar lymphoma with a median patient age of 42 years. There were t...

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Bibliographic Details
Published in:São Paulo medical journal 1999-09, Vol.117 (5), p.215-217
Main Authors: Colleoni, G W, Oliveira, J S, Alves, A C, Borducchi, D M, Segreto, R A, Cervantes, O, Kerbauy, J
Format: Article
Language:English
Subjects:
Adult
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Combined Modality Therapy
Female
Humans
Lymphoma, Non-Hodgkin - drug therapy
Lymphoma, Non-Hodgkin - radiotherapy
Male
Middle Aged
Prognosis
Tonsillar Neoplasms - drug therapy
Tonsillar Neoplasms - radiotherapy
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Summary:There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. We report six cases of primary tonsillar lymphoma with a median patient age of 42 years. There were two lymphoma cases with diffuse large cells, two cases with mixed small and large cells, one with small cells and one indeterminate. They were treated with six cycles of chemotherapy and cervical radiotherapy. All patients achieved durable complete remission. Our data agree with previous reports that suggested that primary tonsillar high-grade B-cell NHL has a good prognosis if aggressively treated.
ISSN:1516-3180
DOI:10.1590/S1516-31801999000500006