Predicting trabecular bone microdamage initiation and accumulation using a non-linear perfect damage model

Abstract Studies evaluating the mechanical behavior of the trabecular microstructure play an important role in our understanding of pathologies such as osteoporosis, and in increasing our understanding of bone fracture and bone adaptation. Understanding of such behavior in bone is important for pred...

Full description

Saved in:
Bibliographic Details
Published in:Medical engineering & physics 2008-07, Vol.30 (6), p.725-732
Main Authors: Kosmopoulos, Victor, Keller, Tony S
Format: Article
Language:English
Subjects:
Biomechanical Phenomena
Bone and Bones - diagnostic imaging
Bone and Bones - injuries
Bone and Bones - pathology
Bone and Bones - physiopathology
Bone Remodeling
Finite Element Analysis
Finite element method
Fractures, Bone - etiology
Fractures, Bone - pathology
Fractures, Bone - physiopathology
Humans
Imaging, Three-Dimensional
Microdamage initiation
Microstructural deformation
Models, Anatomic
Models, Biological
Nonlinear Dynamics
Perfect damage
Radiographic Image Interpretation, Computer-Assisted
Radiology
Tomography, X-Ray Computed
Trabecular bone
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Studies evaluating the mechanical behavior of the trabecular microstructure play an important role in our understanding of pathologies such as osteoporosis, and in increasing our understanding of bone fracture and bone adaptation. Understanding of such behavior in bone is important for predicting and providing early treatment of fractures. The objective of this study is to present a numerical model for studying the initiation and accumulation of trabecular bone microdamage in both the pre- and post-yield regions. A sub-region of human vertebral trabecular bone was analyzed using a uniformly loaded anatomically accurate microstructural three-dimensional finite element model. The evolution of trabecular bone microdamage was governed using a non-linear, modulus reduction, perfect damage approach derived from a generalized plasticity stress–strain law. The model introduced in this paper establishes a history of microdamage evolution in both the pre- and post-yield regions.
ISSN:1350-4533
1873-4030
DOI:10.1016/j.medengphy.2007.02.011