Opportunities at the interface of chemistry and biology

The combination of the tools and principles of chemistry, together with the tools of modern molecular biology, allow us to create complex synthetic and natural molecules, and processes with novel biological, chemical and physical properties. This article illustrates the tremendous opportunity that l...

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Bibliographic Details
Published in:Trends in Cell Biology 1999-12, Vol.9 (12), p.M24-M28
Main Authors: Martin, Andrew B, Schultz, Peter G
Format: Article
Language:English
Subjects:
Antibodies, Catalytic
Biological synthesis
Biology - trends
Chemical
Chemistry - trends
Combinatorial Chemistry Techniques
Evolution, Molecular
Genetic Variation
Humans
Molecular function
Molecular Probe Techniques
Space life sciences
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Summary:The combination of the tools and principles of chemistry, together with the tools of modern molecular biology, allow us to create complex synthetic and natural molecules, and processes with novel biological, chemical and physical properties. This article illustrates the tremendous opportunity that lies at this interface of chemistry and biology by describing a number of examples, ranging from efforts to expand the genetic code of living organisms to the use of combinatorial methods to generate biologically active synthetic molecules.
ISSN:0962-8924
1879-3088
DOI:10.1016/S0962-8924(99)01682-7