An event-related brain potential study of receptive speech comprehension using a modified Token Test

• Published in: Neuropsychologia 1999-12, Vol.37 (13), p.1477-1489
• Main Authors: D’Arcy, R.C.N, Connolly, J.F
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Assessment; Attention; Attention - physiology; Behavioral psychophysiology; Biological and medical sciences; Color Perception - physiology; Dominance, Cerebral - physiology; Electroencephalography; Electrophysiology; Evoked potentials; Evoked Potentials, Auditory - physiology; Female; Fundamental and applied biological sciences. Psychology; Humans; Language; Male; Memory; Neuropsychological Tests; Pattern Recognition, Visual - physiology; Problem Solving - physiology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychomotor Performance - physiology; Speech perception; Speech Perception - physiology
• ISSN: 0028-3932; 1873-3514
• DOI: 10.1016/S0028-3932(99)00057-3

There is a long and distinguished history of evaluating sensory functions with evoked potentials (EPs). However, the clinical utility of event-related brain potentials (ERPs) in the assessment of cognitive functions remains to be established. We present evidence for the efficacy of ERPs in the assessment of speech comprehension. In this normative study, a version of the Token Test (Boller and Vignolo, 1966, Brain, 89, 815–831; De Renzi and Vignolo, 1962, Brain, 85, 665–678) was modified for computer presentation with simultaneous ERP recordings and then administered to a group of healthy individuals ( n=27). A differential neural response pattern to incorrect and correct test items was obtained for the group and, more importantly, this result was also observed reliably at the individual subject level. This research complements on-going efforts in our laboratory to develop innovative measures for patients that are difficult or impossible to assess due to motoric and/or communicative limitations.