Long-term efficacy of fixed CPAP recommended by Autoset® for OSAS

The Autoset autotitration system (Resmed, Australia) was designed as an aid for determination of the effective level of CPAP. Two studies have shown that the 95% pressure centile during a night with Autoset, after excluding any periods with severe leak (P95), was well correlated with the pressure de...

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Bibliographic Details
Published in:Sleep (New York, N.Y.) N.Y.), 1999-12, Vol.22 (8), p.1095-1099
Main Authors: GAGNADOUX, F, RAKOTONANAHARY, D, MARTINS DE ARAUJO, M. T, BARROS-VIEIRA, S, FLEURY, B
Format: Article
Language:English
Subjects:
Biological and medical sciences
Diseases of the upper aerodigestive tract
Ent and stomatology
Female
Follow-Up Studies
Home Care Services
Humans
Long-Term Care
Male
Medical sciences
Middle Aged
Patient Compliance
Positive-Pressure Respiration - methods
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Sleep Apnea, Obstructive - therapy
Titrimetry - instrumentation
Treatment Outcome
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Summary:The Autoset autotitration system (Resmed, Australia) was designed as an aid for determination of the effective level of CPAP. Two studies have shown that the 95% pressure centile during a night with Autoset, after excluding any periods with severe leak (P95), was well correlated with the pressure determined manually according to the reference method. However, the suitability of P95 under Autoset for treatment with conventional CPAP needed to be evaluated outside of the context of titration. The objective of this study was to measure the compliance and efficacy of CPAP at P95 determined by Autoset, after 3 months. Twenty-four patients who had undergone routine autotitration by Autoset under polysomnographic control in the laboratory for previously untreated OSAS were evaluated after 3 months of treatment with CPAP at P95. This evaluation was based on compliance, daily usage, determined by reading the hourly counter, Epworth sleepiness score and home respiratory recording under CPAP. Polysomnography under Autoset showed a significant reduction of abnormal respiratory events (apnea-hypopnea index (AHI): 5.7 (+/-4.6) vs 69.6 (+/-29.8) n/h; p
ISSN:0161-8105
1550-9109
DOI:10.1093/sleep/22.8.1095