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Pathogenicity of microbes associated with cystic fibrosis
Cystic fibrosis patients are exceptionally prone to colonisation by a narrow spectrum of pathogenic bacteria. Since pulmonary infection presently, and for the foreseeable future, plays such a major role in CF lung disease, we review the microbes that are classically associated with CF and the virule...
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Published in: | Microbes and Infection 1999-10, Vol.1 (12), p.1005-1014 |
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container_end_page | 1014 |
container_issue | 12 |
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container_title | Microbes and Infection |
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creator | Hutchison, Michael L. Govan, John R.W. |
description | Cystic fibrosis patients are exceptionally prone to colonisation by a narrow spectrum of pathogenic bacteria. Since pulmonary infection presently, and for the foreseeable future, plays such a major role in CF lung disease, we review the microbes that are classically associated with CF and the virulence, inflammatory potential and resistance mechanisms which contribute to the reduction in life expectancy for colonised CF patients. |
doi_str_mv | 10.1016/S1286-4579(99)80518-8 |
format | article |
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subjects | bacteria Bacterial diseases Bacterial Infections - microbiology Bacterial sepsis Biological and medical sciences Burkholderia cepacia - isolation & purification Burkholderia cepacia - pathogenicity cystic fibrosis Cystic Fibrosis - microbiology Gram-Negative Bacteria - isolation & purification Gram-Negative Bacteria - pathogenicity Haemophilus influenzae - isolation & purification Haemophilus influenzae - pathogenicity Human bacterial diseases Humans infection Infectious diseases Medical sciences Pseudomonas aeruginosa - isolation & purification Pseudomonas aeruginosa - pathogenicity Respiratory System - microbiology Respiratory Tract Infections - microbiology Staphylococcus aureus - pathogenicity Virulence |
title | Pathogenicity of microbes associated with cystic fibrosis |
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