Predictors for recurrence of epileptic seizures in a general epilepsy population

The aim of our study was to identify predictors for recurrence of epileptic seizures in a large county hospital population. We identified 956 patients (18–67 years) with ICD 9 code 345 as primary diagnosis, seen at the Central Hospital of Akershus over 7 years (1987–1994). The diagnosis of epilepsy...

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Bibliographic Details
Published in:Seizure (London, England) England), 1999-12, Vol.8 (8), p.476-479
Main Authors: Lossius, Morten I., Stavem, Knut, Gjerstad, Leif
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Electroencephalography
epilepsy
Epilepsy - diagnosis
Epilepsy - rehabilitation
Female
Hospitalization
Hospitals, County
Humans
Male
Middle Aged
Population Surveillance
Predictive Value of Tests
predictors
Recurrence
recurrence of seizures
Retrospective Studies
Tomography, X-Ray Computed
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Summary:The aim of our study was to identify predictors for recurrence of epileptic seizures in a large county hospital population. We identified 956 patients (18–67 years) with ICD 9 code 345 as primary diagnosis, seen at the Central Hospital of Akershus over 7 years (1987–1994). The diagnosis of epilepsy was confirmed for 696 of the patients. These were divided into two groups: (1) no seizures during the previous year (n= 485) and (2) seizures during the previous year (n= 184). To identify predictors for recurrence of seizures, we used neurologic deficit, number of AEDs used, CT-scan findings, EEG findings, aetiology, gender, age below and above 50 years and comorbidity as independent variables in a logistic regression model. In a univariate analysis, the strongest predictors for recurrence of seizures were: age above 50 years (OR = 5.2;P< 0.0001), known aetiology (OR = 1.4;P= 0.04) and use of two or more AEDs (OR = 5.7;P< 0.0001). In the multivariate analysis age, more than 50 years (OR = 1.7;P= 0.0216) and use of two or more AEDs (OR = 5.6;P< 0.0001) were the only predictors for recurrence of epileptic seizures.
ISSN:1059-1311
1532-2688
DOI:10.1053/seiz.1999.0355