On the combination of photodynamic therapy with ionizing radiation

Ehrlich ascites carcinoma growth and cell damage have been examined after photodynamic therapy (PDT), radiotherapy (RT) and combined treatment. Haematoporphyrin dimethyl ether (HPde) is used as a photosensitizer for PDT and tested as a radiosensitizer for RT. For PDT a non-coherent light source (370...

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Bibliographic Details
Published in:Journal of photochemistry and photobiology. B, Biology Biology, 1999-09, Vol.52 (1), p.35-42
Main Authors: Luksiene, Zivile, Kalvelyte, Audrone, Supino, Rosanna
Format: Article
Language:English
Subjects:
Animals
Apoptosis - drug effects
Apoptosis - radiation effects
Carcinoma, Ehrlich Tumor - drug therapy
Carcinoma, Ehrlich Tumor - pathology
Carcinoma, Ehrlich Tumor - radiotherapy
Cell Division - drug effects
Cell Division - radiation effects
Chromosome Aberrations
Cobalt Radioisotopes
Combined Modality Therapy
Gamma Rays
Haematoporphyrin
Hematoporphyrins - therapeutic use
Mice
Mice, Inbred BALB C
Photochemotherapy
Photodynamic therapy
Photosensitization
Radiation, Ionizing
Radiation-Sensitizing Agents - therapeutic use
Radiosensitization
Radiotherapy
Tumours
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Summary:Ehrlich ascites carcinoma growth and cell damage have been examined after photodynamic therapy (PDT), radiotherapy (RT) and combined treatment. Haematoporphyrin dimethyl ether (HPde) is used as a photosensitizer for PDT and tested as a radiosensitizer for RT. For PDT a non-coherent light source (370< λ
ISSN:1011-1344
1873-2682
DOI:10.1016/S1011-1344(99)00098-6