Hyperbaric oxygen therapy as a prophylactic and treatment against ileus and recurrent intestinal obstruction soon after surgery to relieve adhesive intestinal obstruction

Background and Aim:  Nonoperative management of cases of adhesive intestinal obstruction would be ideal, especially for patients who have recently undergone surgery to relieve the same condition. We aimed to examine whether hyperbaric oxygen (HBO) therapy might have therapeutic potential for the tre...

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Published in:Journal of gastroenterology and hepatology 2008-08, Vol.23 (8pt2), p.e379-e383
Main Authors: Ambiru, Satoshi, Furuyama, Nobuaki, Kimura, Fumio, Shimizu, Hiroaki, Yoshidome, Hiroyuki, Miyazaki, Masaru, Shimada, Hideaki, Ochiai, Takenori
Format: Article
Language:English
Subjects:
adhesive intestinal obstruction
Digestive System Surgical Procedures - adverse effects
Humans
hyperbaric oxygen therapy
Hyperbaric Oxygenation
Intestinal Obstruction - etiology
Intestinal Obstruction - surgery
Intestinal Obstruction - therapy
Intestinal Pseudo-Obstruction - etiology
Intestinal Pseudo-Obstruction - therapy
postoperative paralytic ileus
Recurrence
Tissue Adhesions - surgery
Tissue Adhesions - therapy
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Summary:Background and Aim:  Nonoperative management of cases of adhesive intestinal obstruction would be ideal, especially for patients who have recently undergone surgery to relieve the same condition. We aimed to examine whether hyperbaric oxygen (HBO) therapy might have therapeutic potential for the treatment of postoperative paralytic ileus and recurrent adhesive intestinal obstruction soon after surgery, to relieve adhesive intestinal obstruction, because of its unique mechanisms in these contexts. Methods:  A total of 133 patients were enrolled in the present study. We examined non–per os periods, hospital stay, and clinical course according to the postoperative course of the 133 patients. Results:  After surgical intervention, 75 patients left the hospital without morbidity. Nineteen patients were successfully administered prophylactic HBO therapy to facilitate intestinal motility and to prevent paralytic ileus. The remaining 39 patients suffered from postoperative paralytic ileus or early recurrence of obstruction during the same hospitalization period. The patients who underwent prophylactic HBO therapy had significantly shorter non–per os periods and hospital stays after surgery than those who were not initially given HBO therapy (P 
ISSN:0815-9319
1440-1746
DOI:10.1111/j.1440-1746.2007.05023.x