Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents

Conjugate addition (CA) and allylic alkylation reactions using Grignard reagents are discussed. The mechanistic aspects of copper-promoted CA are investigated.

Saved in:
Bibliographic Details
Published in:Chemical reviews 2008-08, Vol.108 (8), p.2824-2852
Main Authors: Harutyunyan, Syuzanna R, den Hartog, Tim, Geurts, Koen, Minnaard, Adriaan J, Feringa, Ben L
Format: Article
Language:English
Subjects:
Alkylation
Allyl Compounds - chemical synthesis
Allyl Compounds - chemistry
Catalysis
Chemical reactions
Chemistry
Copper
Copper - chemistry
Crystallography, X-Ray
Models, Molecular
Molecular Structure
Organometallic Compounds - chemistry
Stereoisomerism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Conjugate addition (CA) and allylic alkylation reactions using Grignard reagents are discussed. The mechanistic aspects of copper-promoted CA are investigated.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr068424k