Estimates of daily net endogenous acid production in the elderly UK population: analysis of the National Diet and Nutrition Survey (NDNS) of British adults aged 65 years and over

Dietary intake has been shown to influence acid–base balance in human subjects under tightly controlled conditions. However, the net effect of food groups on alkali/acid loading in population groups is unclear. The aims of the present study were to: (1) quantify estimates of daily net endogenous aci...

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Bibliographic Details
Published in:British journal of nutrition 2008-09, Vol.100 (3), p.615-623
Main Authors: Gannon, Richard H. T., Millward, D. Joe, Brown, Jonathan E., Macdonald, Helen M., Lovell, David P., Frassetto, Lynda A., Remer, Thomas, Lanham-New, Susan A.
Format: Article
Language:English
Subjects:
Acid production
Acid-Base Equilibrium
Acidity
Acidosis - etiology
acids
Acid–base balance
adults
Age Factors
Aged
Algorithms
Analysis of Variance
anthropometric measurements
Anthropometry
Biological and medical sciences
British elderly
daily net endogenous acid production
Diet
Diet Records
dietary surveys
elderly
elderly nutrition
endogenous sources
England
estimation
Feeding. Feeding behavior
Female
Food groups
food records
Fundamental and applied biological sciences. Psychology
gender differences
Humans
Male
men
National Diet and Nutrition Survey
Net endogenous acid production
nutrient intake
Nutrition Surveys
Organic acids
Organic loading
Scotland
Sex Factors
Statistics, Nonparametric
Vertebrates: anatomy and physiology, studies on body, several organs or systems
women
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Summary:Dietary intake has been shown to influence acid–base balance in human subjects under tightly controlled conditions. However, the net effect of food groups on alkali/acid loading in population groups is unclear. The aims of the present study were to: (1) quantify estimates of daily net endogenous acid production (NEAP) (mEq/d) in a representative group of British elderly aged 65 years and older; (2) compare and characterise NEAP by specific nutrients and food groups likely to influence dietary acid loading; (3) determine whether geographical location influenced NEAP. The National Diet and Nutrition Survey dataset, consisting of a 4 d weighed record and anthropometric data, was used to estimate dietary acidity. Dietary under-reporters were excluded by analysing only subjects with energy intakes ≥ 1·2 × BMR. NEAP was estimated as the dietary potential renal acid load+organic acid excretion, the latter as a multiple of estimated body surface area. NEAP was lower in women compared with men (P 
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114508901240