Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral fluoroquinolone versus trimethoprim-sulfamethoxazole

We investigated the efficacy of prophylactic use of single dose oral ofloxacin and trimethoprim-sulfamethoxazole regimens for transrectal prostate biopsy in 110 men. In the ofloxacin, trimethoprim-sulfamethoxazole and control groups, urinary infection was found in 2 (4.76%), 3 (6.66%) and 6 (26.08%)...

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Bibliographic Details
Published in:International urology and nephrology 1999, Vol.31 (4), p.491-495
Main Authors: Isen, K, Küpeli, B, Sinik, Z, Sözen, S, Bozkirli, I
Format: Article
Language:English
Subjects:
Administration, Oral
Aged
Anti-Infective Agents - therapeutic use
Anti-Infective Agents, Urinary - therapeutic use
Antibiotic Prophylaxis
Biopsy - adverse effects
Endosonography
Humans
Male
Middle Aged
Ofloxacin - therapeutic use
Prospective Studies
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - pathology
Rectum - diagnostic imaging
Treatment Outcome
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
Urinary Tract Infections - etiology
Urinary Tract Infections - prevention & control
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Summary:We investigated the efficacy of prophylactic use of single dose oral ofloxacin and trimethoprim-sulfamethoxazole regimens for transrectal prostate biopsy in 110 men. In the ofloxacin, trimethoprim-sulfamethoxazole and control groups, urinary infection was found in 2 (4.76%), 3 (6.66%) and 6 (26.08%) patients, respectively. Both of these antibiotic regimens produced a statistically significant reduction in urinary infection (p
ISSN:0301-1623
1573-2584
DOI:10.1023/A:1007115312039