Cathepsin L Functionally Cleaves the Severe Acute Respiratory Syndrome Coronavirus Class I Fusion Protein Upstream of Rather than Adjacent to the Fusion Peptide

• Published in: Journal of Virology 2008-09, Vol.82 (17), p.8887-8890
• Main Authors: JAN BOSCH, Berend, BARTELINK, Willem, ROTTIER, Peter J. M
• Format: Article
• Language: English
• Subjects: Animals; Biological and medical sciences; Cathepsin L; Cathepsins - metabolism; Cathepsins - pharmacology; Cercopithecus aethiops; Cysteine Endopeptidases - metabolism; Cysteine Endopeptidases - pharmacology; Fundamental and applied biological sciences. Psychology; Green Fluorescent Proteins - metabolism; Hydrogen-Ion Concentration; Microbiology; Miscellaneous; Peptides - metabolism; Plasmids; SARS Virus - metabolism; Temperature; Time Factors; Transfection; Trypsin - pharmacology; Vero Cells; Viral Fusion Proteins - classification; Viral Fusion Proteins - metabolism; Virology; Virus-Cell Interactions
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.00415-08

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