Multifocal Granulomatous Hepatitis Caused by Actinobacillus pleuropneumoniae Serotype 2 in Slaughter Pigs

In a survey of 66 894 slaughter pigs, 11 animals from three farms were found to have multifocal granulomatous lesions in the liver, caused by Actinobacillus pleuropneumoniae serotype 2. The lesions consisted of epithelioid cells and multinucleated giant cells, with asteroid bodies and discernible gr...

Full description

Saved in:
Bibliographic Details
Published in:Journal of comparative pathology 2008-08, Vol.139 (2), p.61-66
Main Authors: Ohba, T., Shibahara, T., Kobayashi, H., Takashima, A., Nagoshi, M., Osanai, R., Kubo, M.
Format: Article
Language:English
Subjects:
Actinobacillus Infections - pathology
Actinobacillus Infections - veterinary
Actinobacillus pleuropneumoniae
Animals
asteroid body
bacterial infection
Granuloma - microbiology
Granuloma - pathology
granulomatous hepatitis
Hepatitis, Animal - microbiology
Hepatitis, Animal - pathology
Immunohistochemistry
pig
Pleuropneumonia - pathology
Pleuropneumonia - veterinary
porcine pneumonia
Spleen - pathology
Swine
Swine Diseases - microbiology
Swine Diseases - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In a survey of 66 894 slaughter pigs, 11 animals from three farms were found to have multifocal granulomatous lesions in the liver, caused by Actinobacillus pleuropneumoniae serotype 2. The lesions consisted of epithelioid cells and multinucleated giant cells, with asteroid bodies and discernible gram-negative bacteria. Lymph nodes and spleen were occasionally affected. The results suggested that haematogenous spread had occurred from pre-existing pulmonary infections.
ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2008.04.003