Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases

Summary Usual interstitial pneumonia is an almost uniformly fatal form of fibrosing interstitial lung disease. It is the most common idiopathic interstitial pneumonia, and currently, there is no effective therapy. Lung biopsy is often needed for diagnosis, and pathologists must be able to recognize...

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Bibliographic Details
Published in:Human pathology 2008-09, Vol.39 (9), p.1275-1294
Main Authors: Katzenstein, Anna-Luise A., MD, Mukhopadhyay, Sanjay, MD, Myers, Jeffrey L., MD
Format: Article
Language:English
Subjects:
Adult
Alveolitis, Extrinsic Allergic - pathology
Biological and medical sciences
Biopsy
Diagnosis, Differential
Humans
Hypersensitivity pneumonia
Idiopathic interstitial pneumonia
Interstitial fibrosis
Investigative techniques, diagnostic techniques (general aspects)
Lung - pathology
Lung Diseases, Interstitial - diagnosis
Lung Diseases, Interstitial - pathology
Male
Medical sciences
Nonspecific interstitial pneumonia
NSIP
Pathology
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Pneumology
Pulmonary Fibrosis - pathology
Respiratory system : syndromes and miscellaneous diseases
UIP
Usual interstitial pneumonia
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Summary:Summary Usual interstitial pneumonia is an almost uniformly fatal form of fibrosing interstitial lung disease. It is the most common idiopathic interstitial pneumonia, and currently, there is no effective therapy. Lung biopsy is often needed for diagnosis, and pathologists must be able to recognize its features and distinguish it from other interstitial lung diseases that have a better prognosis and a more favorable response to therapy. This review is an attempt to clarify the diagnostic pathologic features of usual interstitial pneumonia and to provide guidelines for its distinction from other interstitial lung diseases that enter the differential diagnosis.
ISSN:0046-8177
1532-8392
DOI:10.1016/j.humpath.2008.05.009