More on Management of Choroid Plexus Cysts in the Mid-Trimester Fetus

• Published in: Australian & New Zealand journal of obstetrics & gynaecology 1999-11, Vol.39 (4), p.454-457
• Main Authors: de Crespigny, L, Savulescu, J, Sheffield, L J
• Format: Article
• Language: English
• Subjects: Brain Diseases - diagnosis; Choroid Plexus; Cost-Benefit Analysis; Cysts - diagnosis; Female; Fetal Diseases - diagnosis; Humans; Pregnancy; Pregnancy Trimester, Second; Prenatal Diagnosis; Risk Assessment
• ISSN: 0004-8666; 1479-828X
• DOI: 10.1111/j.1479-828X.1999.tb03131.x

EDITORIAL COMMENT: We have published this pair of letters as a feature rather than in the correspondence column so it will not be lost to reference in the literature. Readers are also referred to a recently published review of the world literature concerning the risks of trisomies 18 and 21 in the second‐trimester fetus with an isolated choroid plexus cyst (A). This study concluded that ‘the likelihood of trisomy 18 was 13.8 times greater than the a priori risk in fetuses with isolated choroid plexus cysts diagnosed in the second trimester. However, the likelihood of trisomy 21 was not significantly greater than the a priori risk with isolated choroid plexus cysts.’ N.B. (A) Yoder PR, Sabbagha RE, Gross SJ, Zelop CM. The second‐trimester fetus with isolated choroid plexus cysts: A meta‐analysis of risk of trisomies 18 and 21. Obstet Gynecol 1999; 93: 869–872 1. Choong S, Meagher S, Management of choroid plexus cysts in the mid‐trimester fetus Aust NZ J Obstet Gynecol 1999; 39: 7–11 2. Goldstein H, Philip J. A cost‐benefit analysis of prenatal diagnosis by amniocentesis in Denmark. Clinical Genetics 1990; 37: 24–263 3. Gupta J, Thornton J, Lilford R. Management of fetal choroid plexus cyst. Br J Obstet Gynaecol 1997; 104: 881–886. 4. Gratton R, Hogge W, Ashton C. Choroid plexus cysts and Trisomy 18: Risk modification based on maternal age and multiple‐marker screening. Am J Obstet Gynecol 1996; 175: 1493–1497 Associate Professor Lachlan de Crespigny, Head of Ultrasound, Royal Women's Hospital, Carlton, Melbourne and Associate Professor Julian Savulescu Director, Ethics Unit, The Murdoch Institute, Royal Children's Hospital, Parkville, Melbourne and Dr Leslie J Sheffield, Director of Education and Training, Victorian Clinical Genetic Services, Royal Children's Hospital, Parkville, Melbourne.