The effects of examination stress on salivary cortisol, immunoglobulin A, and chromogranin A in nursing students

This study aimed to assess the effects of examination stress on salivary cortisol, immunoglobulin A (IgA), and chromogranin A (CgA) in nursing students. Saliva samples were collected from 15 healthy females before and immediately after the one-hour examination, and two hours after the examination. S...

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Bibliographic Details
Published in:Biomedical Research 2008, Vol.29(4), pp.221-224
Main Authors: Takatsuji, Koichi, Sugimoto, Yoshie, Ishizaki, Shoko, Ozaki, Yasuka, Matsuyama, Etsuko, Yamaguchi, Yukari
Format: Article
Language:English
Subjects:
Chromogranin A - metabolism
Educational Measurement
Enzyme-Linked Immunosorbent Assay
Female
Humans
Hydrocortisone - metabolism
Immunoglobulin A - metabolism
Psychoneuroimmunology
Saliva - chemistry
Saliva - metabolism
Stress, Physiological - metabolism
Students, Nursing - psychology
Universities
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Summary:This study aimed to assess the effects of examination stress on salivary cortisol, immunoglobulin A (IgA), and chromogranin A (CgA) in nursing students. Saliva samples were collected from 15 healthy females before and immediately after the one-hour examination, and two hours after the examination. Salivary cortisol, IgA, and CgA concentrations were determined by enzyme-linked immunosorbent assay. Both IgA and CgA concentrations statistically increased immediately after the examination (P < 0.05) and decreased two hours after the examination. No significant differences were observed between before and after the examination in the salivary cortisol concentration. These findings suggest that the acute stress due to the examination is associated with raised salivary IgA and CgA, but not cortisol.
ISSN:0388-6107
1880-313X
DOI:10.2220/biomedres.29.221