Usefulness of P-Wave Dispersion in Standard Twelve-Lead Electrocardiography to Predict Transition from Paroxysmal to Persistent Atrial Fibrillation

A prospective study was conducted to investigate the validity of the hypothesis that P-wave dispersion (Pd) may be a clinically useful predictor of progression from paroxysmal to persistent atrial fibrillation (AF). Two hundred four consecutive patients with a diagnosis of paroxysmal AF were studied...

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Bibliographic Details
Published in:The American journal of cardiology 2008-09, Vol.102 (5), p.573-577
Main Authors: Koide, Yasushi, MD, Yotsukura, Masayuki, MD, Ando, Harunori, MD, Aoki, Syuiti, MD, Suzuki, Takaomi, MD, Sakata, Konomi, MD, Ootomo, Eiiti, MD, Yoshino, Hideaki, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Atrial Fibrillation - diagnosis
Atrial Fibrillation - physiopathology
Biological and medical sciences
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Confidence Intervals
Disease Progression
Echocardiography - methods
Electrocardiography - methods
Female
Follow-Up Studies
Heart
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Humans
Hypotheses
Male
Medical sciences
Middle Aged
Predictive Value of Tests
Prospective Studies
Regression Analysis
ROC Curve
Severity of Illness Index
Tachycardia, Paroxysmal - diagnosis
Tachycardia, Paroxysmal - physiopathology
Time Factors
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Summary:A prospective study was conducted to investigate the validity of the hypothesis that P-wave dispersion (Pd) may be a clinically useful predictor of progression from paroxysmal to persistent atrial fibrillation (AF). Two hundred four consecutive patients with a diagnosis of paroxysmal AF were studied. Standard 12-lead electrocardiography and echocardiography were performed on all patients at the time of entry into the study. Pd was measured as the difference between maximum and minimum P-wave duration in any of the 12 leads. Mean follow-up was 66 ± 8 months. Group I included patients (n = 132) in whom paroxysmal AF did not progress to persistent AF, and group II included those (n = 72) who developed persistent AF. In group II, age, percentage of men, percentage of patients with diabetes mellitus, maximum P-wave duration, Pd, and left atrial dimension were significantly higher than in group I (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2008.04.065