The human dendritic cell marker CD83 maps to chromosome 6p23

The chromosomal localization of the human CD83 gene was determined using somatic cell hybrids, a radiation hybrid mapping panel and FISH analysis on human metaphase chromosomes. PCR-based analysis of a single chromosome hybrid panel identified the presence of the CD83 gene on human chromosome 6 and...

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Bibliographic Details
Published in:Annals of human genetics 1999-03, Vol.63 (2), p.181-183
Main Authors: BERCHTOLD, S., JONES, T., MÜHL-ZÜRBES, P., SHEER, D., SCHULER, G., STEINKASSERER, A.
Format: Article
Language:English
Subjects:
Antigens, CD
Biological and medical sciences
Biomarkers
CD83 Antigen
Chromosome Banding
Chromosome Mapping
Chromosomes, Human, Pair 6 - genetics
Dendritic Cells - metabolism
DNA - chemistry
DNA - genetics
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Genetics of the immune response
Humans
Immunobiology
Immunoglobulins - genetics
In Situ Hybridization, Fluorescence
Membrane Glycoproteins - genetics
Molecular Sequence Data
Sequence Analysis, DNA
SHORT COMMUNICATION
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Summary:The chromosomal localization of the human CD83 gene was determined using somatic cell hybrids, a radiation hybrid mapping panel and FISH analysis on human metaphase chromosomes. PCR-based analysis of a single chromosome hybrid panel identified the presence of the CD83 gene on human chromosome 6 and subsequent analysis of the Genebridge4 radiation panel located the gene between AFMa192wg9 and AFMb322wd1 with a lod score of 9.2. Finally, using FISH analysis the CD83 gene was localized to chromosome 6 band p23.
ISSN:0003-4800
1469-1809
DOI:10.1046/j.1469-1809.1999.6320181.x