Magnetic resonance imaging of experimentally-induced sialadenitis in rat submandibular glands

To correlate the features of magnetic resonance (MR) images of experimentally induced obstructive sialadenitis in rat submandibular glands with the histopathological changes. Changes in MR images of ligated and non-ligated rat submandibular glands were compared with the histopathological changes and...

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Bibliographic Details
Published in:Dento-maxillo-facial radiology 1999-11, Vol.28 (6), p.330-337
Main Authors: Shimizu, M, Sekine, N, Nishimura, K, Tokumori, K, Saitoh, M, Kanda, S
Format: Article
Language:English
Subjects:
Animals
Dentistry
Disease Progression
Ligation
Magnetic Resonance Imaging - methods
Male
Rats
Rats, Sprague-Dawley
Sialadenitis - pathology
Signal Processing, Computer-Assisted
Submandibular Gland Diseases - pathology
Time Factors
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Summary:To correlate the features of magnetic resonance (MR) images of experimentally induced obstructive sialadenitis in rat submandibular glands with the histopathological changes. Changes in MR images of ligated and non-ligated rat submandibular glands were compared with the histopathological changes and wet weight ratios. Spin echo T1 weighted images (SE T1WI), fast spin echo T2 weighted images (FSE T2WI), and gradient echo T2 weighted images (GE T2WI) were obtained at 1, 2, 3, 4, 5, 7 and 21 days after duct ligation with a 0.3 T MR imaging system. There was a significant difference (P
ISSN:0250-832X
DOI:10.1038/sj.dmfr.4600470