Asymmetric intermolecular Stetter reactions catalyzed by a novel triazolium derived N-heterocyclic carbene

The asymmetric intermolecular Stetter reaction is catalyzed by a novel triazolium salt derived N-heterocyclic carbene leading to 1,4-diketones in moderate to excellent yields (49-98%) and moderate to good enantioselectivities (56-78% ee), which could be enhanced by one recrystallization to excellent...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2008-09 (34), p.3989-3991
Main Authors: Enders, Dieter, Han, Jianwei, Henseler, Alexander
Format: Article
Language:English
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Summary:The asymmetric intermolecular Stetter reaction is catalyzed by a novel triazolium salt derived N-heterocyclic carbene leading to 1,4-diketones in moderate to excellent yields (49-98%) and moderate to good enantioselectivities (56-78% ee), which could be enhanced by one recrystallization to excellent levels (90-99% ee).
ISSN:1359-7345
1364-548X
DOI:10.1039/b809913h