Reference values of plasma oxalate in children and adolescents

Oxalate homeostasis is a derivative of absorption and transportation in the digestive system and renal/intestinal excretion of oxalate. The objective of this cross-sectional study was to determine normative values of plasma oxalate in relation to age, gender, and body size. A group of 1,260 healthy...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2008-10, Vol.23 (10), p.1787-1794
Main Authors: Porowski, Tadeusz, Zoch-Zwierz, Walentyna, Konstantynowicz, Jerzy, Korzeniecka-Kozerska, Agata, Michaluk-Skutnik, Joanna, Porowska, Halina
Format: Article
Language:English
Subjects:
Adolescent
Age
Child
Child, Preschool
Female
Gender
Humans
Kidneys
Male
Medicine & Public Health
Metabolism
Nephrology
Original Article
Oxalic Acid - blood
Pediatrics
Plasma
Reference Values
Teenagers
Uric acid
Urology
White people
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Summary:Oxalate homeostasis is a derivative of absorption and transportation in the digestive system and renal/intestinal excretion of oxalate. The objective of this cross-sectional study was to determine normative values of plasma oxalate in relation to age, gender, and body size. A group of 1,260 healthy Caucasian children and adolescents aged 3 months to 18 years [mean ± standard deviation (SD) 10.5 ± 4.3] was studied. Each 1-year group comprised 70 subjects. Oxalate levels were assessed in blood plasma samples obtained from fasted individuals using the precipitation–enzymatic method with oxalate oxidase. Median oxalate levels in healthy infants was 3.20 µmol/L (5th–95th percentiles: 1.56–5.58) and was higher compared with older children [2.50 µmol/L (5th–95th percentiles: 0.95–5.74); p  
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-008-0889-8