Assessing the effect of increasing injection activity for myocardial perfusion imaging in overweight patients

In our previous publication, we proposed to increase the injection activity for overweight patients. We have now implemented this for our patients, i.e. increasing the activity for patients above 99 kg. In the present study, we audited whether this increased activity for overweight patients improved...

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Bibliographic Details
Published in:British journal of radiology 2008-09, Vol.81 (969), p.730-734
Main Authors: NOTGHI, A, SUNDRAM, F. X, O'BRIEN, J. W, SMITH, N. B
Format: Article
Language:English
Subjects:
Algorithms
Biological and medical sciences
Body Weight
Clinical Protocols
Coronary Circulation - physiology
Female
Heart - diagnostic imaging
Humans
Injections
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Metabolic diseases
Obesity
Organophosphorus Compounds
Organotechnetium Compounds
Overweight - diagnostic imaging
Radiographic Image Enhancement - methods
Radiopharmaceuticals - administration & dosage
Reproducibility of Results
Tomography, Emission-Computed, Single-Photon - methods
Ventricular Dysfunction - diagnostic imaging
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Summary:In our previous publication, we proposed to increase the injection activity for overweight patients. We have now implemented this for our patients, i.e. increasing the activity for patients above 99 kg. In the present study, we audited whether this increased activity for overweight patients improved the myocardial counts effectively and also whether it improved the image quality for these patients. 125 consecutive normal myocardial perfusion studies were included into the study. The total left ventricular myocardial count was calculated, as was the total left ventricular myocardial volume using the Cedar Sinai QPS program. The myocardial count per millilitre of the myocardium (c ml(-1)) was correlated with patient weight using regression analysis. There was no significant difference (p = 0.120) among the mean myocardial counts for patients over 99 kg (n = 40, 1548 c ml(-1)) compared with patients in the 70-79 kg range (n = 26, 1746 c ml(-1)). This indicates that the previously proposed algorithm for adjusting injection activity maintains the count density in the myocardium and should be used for all patients over 99 kg. There was, however, a significant steady decrease with increased weight in the myocardial counts for patients under 100 kg (p
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr/60645843