Management of Chronic Daily Headache Utilizing a Uniform Treatment Pathway

Objective.—To determine if the use of a uniform treatment pathway might be effective in treating patients with primary chronic daily headache. Methods.—Thirty‐three consecutive patients with primary chronic daily headache were managed according to a treatment pathway which involved sequential admini...

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Bibliographic Details
Published in:Headache 1999-10, Vol.39 (9), p.650-653
Main Author: Rothrock, John F.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Amitriptyline - therapeutic use
Analgesics
Analgesics, Non-Narcotic - therapeutic use
Analgesics, Opioid - therapeutic use
Biological and medical sciences
Chronic Disease
Drug Therapy, Combination
Female
GABA Agents - therapeutic use
Headache - drug therapy
Humans
Male
Medical sciences
Methadone - therapeutic use
Middle Aged
Neuropharmacology
Pharmacology. Drug treatments
Phenelzine - therapeutic use
primary chronic daily headache
uniform treatment pathway
Valproic Acid - therapeutic use
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Summary:Objective.—To determine if the use of a uniform treatment pathway might be effective in treating patients with primary chronic daily headache. Methods.—Thirty‐three consecutive patients with primary chronic daily headache were managed according to a treatment pathway which involved sequential administration of divalproex sodium, amitriptyline, amitriptyline plus phenelzine, or methadone. Results.—Twenty‐two patients (67%) reported a 50% or greater reduction in headache days per month following initiation of treatment. Most positive treatment responses (17 [77%] of 22) were attributed to divalproex sodium. Conclusion.—Implementation of a uniform treatment pathway may result in significant clinical improvement in a sizable proportion of patients with chronic daily headache.
ISSN:0017-8748
1526-4610
DOI:10.1046/j.1526-4610.1999.3909650.x