Mode of delivery and neonatal survival of infants with gastroschisis in Australia and New Zealand

Abstract Objective The aim of the study was to examine the short-term outcome of infants with gastroschisis by route of delivery, comparing vaginal delivery vs elective and emergency cesarean delivery (CD). Methods Six hundred thirty-one infants with gastroschisis ( International Classification of D...

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Bibliographic Details
Published in:Journal of pediatric surgery 2008-09, Vol.43 (9), p.1685-1690
Main Authors: Abdel-Latif, Mohamed E, Bolisetty, Srinivas, Abeywardana, Samanthi, Lui, Kei
Format: Article
Language:English
Subjects:
Adult
Australia
Cesarean delivery
Cesarean Section
Delivery, Obstetric
Emergency Treatment
Female
Gastroschisis
Gastroschisis - mortality
Humans
Infant, Newborn
Male
New Zealand
Pediatrics
Retrospective Studies
Surgery
Survival Rate
Vaginal delivery
Ventral wall defect
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Summary:Abstract Objective The aim of the study was to examine the short-term outcome of infants with gastroschisis by route of delivery, comparing vaginal delivery vs elective and emergency cesarean delivery (CD). Methods Six hundred thirty-one infants with gastroschisis ( International Classification of Diseases, 10th Revision : Q79.3) were admitted to the Australian and New Zealand Neonatal Network during 1997 to 2005. Multivariate Cox proportional hazards regression analysis was performed to adjust for case-mix and significant baseline characteristics. Results During the study period, 631 infants with gastroschisis were admitted to the collaborating centers. Of these, 343 (54.4%) infants were delivered vaginally, whereas 288 (45.6%) were delivered by cesarean birth. Of the latter, 148 (23.4%) were elective and 140 (22.2%) were emergency. There was an increasing trend of CD from 41.1% in 1997 to 69.0% in 2005. Forty-seven (7.4%) infants died; 30 (8.7%) in the vaginal, 9 (6.4%) in the emergency, and 8 (5.4%) in the elective CD group. There was no difference in rate of proven infection, duration of ventilation, or length of neonatal intensive care unit stay between the 3 groups. After controlling for prematurity, low birth weight, and outborn birth, the risk for neonatal demise was similar in both the vaginal and CD infants (adjusted hazard ratio, 1.486; 95% confidence interval, 0.814-2.713; P = .197). Stratifying the CD (emergency vs elective) gave similar results. Conclusion Infants with gastroschisis appear to be safely delivered vaginally.
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2008.03.053