T‐cell PTLD presenting as acalculous cholecystitis

:  We report a five‐yr‐old child, presenting three yr after heart transplant with acalculous cholecystitis. Histology revealed EBV negative T‐cell PTLD. The disease involved the gallbladder, liver, lungs, and mesenteric lymph nodes. He was treated with chemotherapy, went into remission, but relapsed...

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Bibliographic Details
Published in:Pediatric transplantation 2008-09, Vol.12 (6), p.717-720
Main Authors: Miloh, Tamir, Magid, Margret, Yurovitsky, Alyssa, Strauchen, James, Arnon, Ronen, Kerkar, Nanda, Rosenberg, Henrietta, Joashi, Umesh, Bhojwani, Deepa
Format: Article
Language:English
Subjects:
acalculous
Acalculous Cholecystitis - diagnosis
Acalculous Cholecystitis - immunology
Biological and medical sciences
Cardiomyopathy, Dilated - therapy
Child
cholecystitis
Diagnosis, Differential
Epstein-Barr virus
Fatal Outcome
gallbladder
Gallbladder - pathology
Gastroenterology. Liver. Pancreas. Abdomen
Heart Transplantation - adverse effects
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Liver. Biliary tract. Portal circulation. Exocrine pancreas
lymphoproliferative
Lymphoproliferative Disorders - diagnosis
Lymphoproliferative Disorders - immunology
Male
Medical sciences
Other diseases. Semiology
post‐transplant
Remission Induction
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
T-Lymphocytes - immunology
Treatment Outcome
T‐cell PTLD
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Description
Summary::  We report a five‐yr‐old child, presenting three yr after heart transplant with acalculous cholecystitis. Histology revealed EBV negative T‐cell PTLD. The disease involved the gallbladder, liver, lungs, and mesenteric lymph nodes. He was treated with chemotherapy, went into remission, but relapsed after 11 months and died.
ISSN:1397-3142
1399-3046
DOI:10.1111/j.1399-3046.2007.00843.x