Spirometric reference values from a sample of the general U.S. population

Spirometric reference values for Caucasians, African-Americans, and Mexican-Americans 8 to 80 yr of age were developed from 7,429 asymptomatic, lifelong nonsmoking participants in the third National Health and Nutrition Examination Survey (NHANES III). Spirometry examinations followed the 1987 Ameri...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 1999, Vol.159 (1), p.179-187
Main Authors: HANKINSON, J. L, ODENCRANTZ, J. R, FEDAN, K. B
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Analysis. Health state
Biological and medical sciences
Black or African American
Black People
Body Height - physiology
Child
Epidemiology
Female
Forced Expiratory Volume - physiology
General aspects
Humans
Male
Medical sciences
Mexican Americans
Middle Aged
Nutrition Surveys
Public health. Hygiene
Public health. Hygiene-occupational medicine
Reference Values
Respiration
Spirometry
United States
Vital Capacity - physiology
White People
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Summary:Spirometric reference values for Caucasians, African-Americans, and Mexican-Americans 8 to 80 yr of age were developed from 7,429 asymptomatic, lifelong nonsmoking participants in the third National Health and Nutrition Examination Survey (NHANES III). Spirometry examinations followed the 1987 American Thoracic Society recommendations, and the quality of the data was continuously monitored and maintained. Caucasian subjects had higher mean FVC and FEV1 values than did Mexican-American and African-American subjects across the entire age range. However, Caucasian and Mexican-American subjects had similar FVC and FEV1 values with respect to height, and African-American subjects had lower values. These differences may be partially due to differences in body build: observed Mexican-Americans were shorter than Caucasian subjects of the same age, and African-Americans on average have a smaller trunk:leg ratio than do Caucasians. Reference values and lower limits of normal were derived using a piecewise polynomial model with age and height as predictors. These reference values encompass a wide age range for three race/ethnic groups and should prove useful for diagnostic and research purposes.
ISSN:1073-449X
1535-4970
DOI:10.1164/ajrccm.159.1.9712108