Functional recovery of subepicardial myocardial tissue in transmural myocardial infarction after successful reperfusion : An important contribution to the improvement of regional and global left ventricular function

The transmural extent of myocardial necrosis after an acute coronary artery occlusion can vary considerably. The contribution of residual subepicardial viable myocardium to global left ventricular function is largely unknown. We studied 12 patients with single-vessel disease 1 week after successful...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1999-01, Vol.99 (1), p.36-43
Main Authors: BOGAERT, J, MAES, A, DE WERF, F. V, BOSMANS, H, HERREGODS, M.-C, NUYTS, J, DESMET, W, MORTELMANS, L, MARCHAL, G, RADEMAKERS, F. E
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Biological and medical sciences
Cardiology. Vascular system
Case-Control Studies
Coronary Angiography
Coronary heart disease
Female
Heart
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - pathology
Myocardial Infarction - physiopathology
Myocardial Reperfusion
Necrosis
Pericardium - physiopathology
Reproducibility of Results
Tomography, Emission-Computed
Treatment Outcome
Ventricular Function, Left - physiology
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Summary:The transmural extent of myocardial necrosis after an acute coronary artery occlusion can vary considerably. The contribution of residual subepicardial viable myocardium to global left ventricular function is largely unknown. We studied 12 patients with single-vessel disease 1 week after successful reperfusion of a first transmural anterior myocardial infarction (MI). With PET, myocardial blood flow (MBF) and glucose metabolism were measured regionally, and the viability was graded as normal, mismatch, or match with severely (
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.99.1.36