Pigmented purpura-like eruption as cutaneous sign of mycosis fungoides with autoimmune purpura

We describe the clinical and laboratory findings of a young man with mycosis fungoides. The disease was associated, since the early stages, with autoimmune purpura. Interferon alfa (IFN-α) administration improved this patient’s condition, both the purpuric eruption and patchy cutaneous lesions, thus...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 1999-02, Vol.40 (2), p.298-299
Main Authors: Puddu, Pietro, Ferranti, Giulio, Frezzolini, Alessandra, Colonna, Laura, Cianchini, Giuseppe
Format: Article
Language:English
Subjects:
Adolescent
Autoantibodies - blood
Autoimmune Diseases - diagnosis
Autoimmune Diseases - immunology
Autoimmune Diseases - pathology
Biological and medical sciences
Biopsy
Blood Platelets - immunology
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Mycosis Fungoides - diagnosis
Mycosis Fungoides - immunology
Mycosis Fungoides - pathology
Paraneoplastic Syndromes - diagnosis
Paraneoplastic Syndromes - immunology
Paraneoplastic Syndromes - pathology
Purpura, Thrombocytopenic, Idiopathic - diagnosis
Purpura, Thrombocytopenic, Idiopathic - immunology
Purpura, Thrombocytopenic, Idiopathic - pathology
Skin - immunology
Skin - pathology
Skin Neoplasms - diagnosis
Skin Neoplasms - immunology
Skin Neoplasms - pathology
T-Lymphocytes - immunology
T-Lymphocytes - pathology
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Summary:We describe the clinical and laboratory findings of a young man with mycosis fungoides. The disease was associated, since the early stages, with autoimmune purpura. Interferon alfa (IFN-α) administration improved this patient’s condition, both the purpuric eruption and patchy cutaneous lesions, thus suggesting T-cell abnormalities may be responsible for the development of the disease. (J Am Acad Dermatol 1999;40:298-9.)
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(99)70469-X