Mechanics and Composition of Human Subcutaneous Resistance Arteries in Essential Hypertension

Mechanical properties of arteries are altered in some rat models of hypertension, and this may influence peripheral resistance and blood pressure as well as some of the complications of hypertension. It has usually been assumed that arterial wall stiffness is increased in hypertension, although rece...

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Bibliographic Details
Published in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 1999-01, Vol.33 (1S Suppl), p.569-574
Main Authors: Intengan, Hope D, Deng, Li Y, Li, Jin S, Schiffrin, Ernesto L
Format: Article
Language:English
Subjects:
Adult
Aged
Animals
Arterial hypertension. Arterial hypotension
Arteries - pathology
Arteries - physiology
Arteries - physiopathology
Arterioles - pathology
Arterioles - physiology
Arterioles - physiopathology
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure
Cardiology. Vascular system
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Elasticity
Female
Humans
Hypertension - physiopathology
Male
Medical sciences
Middle Aged
Rats
Skin - blood supply
Stress, Mechanical
Vascular Resistance - physiology
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Summary:Mechanical properties of arteries are altered in some rat models of hypertension, and this may influence peripheral resistance and blood pressure as well as some of the complications of hypertension. It has usually been assumed that arterial wall stiffness is increased in hypertension, although recent studies suggest that this may not necessarily be the case in large arteries. We determined whether the mechanics of human resistance arteries are altered in hypertension. Subcutaneous resistance arteries (lumen diameter
ISSN:0194-911X
1524-4563
DOI:10.1161/01.hyp.33.1.569