Epidemiology of Drug-resistant Tuberculosis in Texas

During 1987–1996, over 22,000 tuberculosis cases were reported in Texas, at an average annual incidence rate of 12.5 cases per 100,000 population. Counties with the highest rates were located along the Mexico-Texas border and in northwestern Texas. Nine percent of cases were resistant to at least on...

Full description

Saved in:
Bibliographic Details
Published in:American journal of epidemiology 1999-02, Vol.149 (4), p.359-365
Main Authors: Taylor, Jeffery Paul, Bergmire-Sweat, David, Suarez, Lucina
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
AIDS-Related Opportunistic Infections - drug therapy
AIDS-Related Opportunistic Infections - epidemiology
AIDS/HIV
Antitubercular Agents - therapeutic use
Bacterial diseases
Biological and medical sciences
Child
Child, Preschool
Cross-Sectional Studies
drug resistance
Drug Therapy, Combination
Female
Human bacterial diseases
Humans
Incidence
Infant
Infectious diseases
Male
Medical sciences
Middle Aged
Risk
risk factors
Texas - epidemiology
tuberculosis
Tuberculosis and atypical mycobacterial infections
Tuberculosis, Multidrug-Resistant - drug therapy
Tuberculosis, Multidrug-Resistant - epidemiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:During 1987–1996, over 22,000 tuberculosis cases were reported in Texas, at an average annual incidence rate of 12.5 cases per 100,000 population. Counties with the highest rates were located along the Mexico-Texas border and in northwestern Texas. Nine percent of cases were resistant to at least one of the five first-line antituberculosis drugs used for treatment. Almost 5 percent (4.6%) were resistant to isoniazid, either alone or in combination with other antibiotics; 2.3% were resistant to rifampin; and only 1.3% were resistant to both isoniazid and rifampin. Being a recurrent case, being foreign-born, being 20–39 years of age, and residing in a Mexico-Texas border county were independent risk factors for isoniazid resistance and rifampin resistance. Tuberculosis patients with human immunodeficiency virus (HIV) infection were more likely to have rifampin resistance and less likely to have isoniazid resistance than patients without HIV infection. Factors associated with multi-drug-resistant tuberculosis included a history of previous tuberculosis (relative risk (RR) = 4.91, 95% confidence interval (CI) 3.5–6.8), non-US birth (RR = 2.69, 95% CI 2.1–3.5), age younger than 20 years (RR = 1.97, 95% CI 1.1–3.5), age 20–39 years (RR = 1.82, 95% CI 1.3–2.6), and residence in a Mexico-Texas border county (RR = 2.33, 95% CI 1.8–3.1). Am J Epidemiol 1999; 149:359–65.
ISSN:0002-9262
1476-6256
DOI:10.1093/oxfordjournals.aje.a009821