An array of Pt-tip microelectrodes for extracellular monitoring of activity of brain slices

A microelectrode array (MEA) consisting of 34 silicon nitride passivated Pt-tip microelectrodes embedded on a perforated silicon substrate (porosity 35%) has been realized. The electrodes are 47 μm high, of which only the top 15 μm are exposed Pt-tips having a curvature of 0.5 μm. The MEA is intende...

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Published in:Biosensors & bioelectronics 1999, Vol.14 (1), p.61-65
Main Authors: Thiébaud, Pierre, Beuret, Cynthia, Koudelka-Hep, Milena, Bove, Marco, Martinoia, Sergio, Grattarola, Massimo, Jahnsen, Henrik, Rebaudo, Renata, Balestrino, Maurizio, Zimmer, Jens, Dupont, Yves
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Biosensors
Brain
Brain - physiology
Electric Impedance
Electrophysiology
extracellular recording
Fundamental and applied biological sciences. Psychology
General aspects. Models. Methods
impedance
In Vitro Techniques
microelectrode arrays
Microelectrodes
Microscopy, Electron, Scanning
Passivation
Platinum
Pt-tip microelectrode
Silicon
Silicon nitride
Vertebrates: nervous system and sense organs
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container_issue 1
container_start_page 61
container_title Biosensors & bioelectronics
container_volume 14
creator Thiébaud, Pierre
Beuret, Cynthia
Koudelka-Hep, Milena
Bove, Marco
Martinoia, Sergio
Grattarola, Massimo
Jahnsen, Henrik
Rebaudo, Renata
Balestrino, Maurizio
Zimmer, Jens
Dupont, Yves
description A microelectrode array (MEA) consisting of 34 silicon nitride passivated Pt-tip microelectrodes embedded on a perforated silicon substrate (porosity 35%) has been realized. The electrodes are 47 μm high, of which only the top 15 μm are exposed Pt-tips having a curvature of 0.5 μm. The MEA is intended for extracellular recordings of brain slices in vitro. Here we report the fabrication, characterization and initial electrophysiological evaluation of the first generation of Pt-tip MEAs.
doi_str_mv 10.1016/S0956-5663(98)00098-0
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source ScienceDirect Freedom Collection
subjects Animals
Biological and medical sciences
Biosensors
Brain
Brain - physiology
Electric Impedance
Electrophysiology
extracellular recording
Fundamental and applied biological sciences. Psychology
General aspects. Models. Methods
impedance
In Vitro Techniques
microelectrode arrays
Microelectrodes
Microscopy, Electron, Scanning
Passivation
Platinum
Pt-tip microelectrode
Silicon
Silicon nitride
Vertebrates: nervous system and sense organs
title An array of Pt-tip microelectrodes for extracellular monitoring of activity of brain slices
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